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Relation between left atrial wall composition by late gadolinium enhancement and complex fractionated atrial electrograms in patients with persistent atrial fibrillation: influence of non-fibrotic…

Overview of attention for article published in The International Journal of Cardiovascular Imaging, May 2015
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Title
Relation between left atrial wall composition by late gadolinium enhancement and complex fractionated atrial electrograms in patients with persistent atrial fibrillation: influence of non-fibrotic substrate in the left atrium
Published in
The International Journal of Cardiovascular Imaging, May 2015
DOI 10.1007/s10554-015-0675-1
Pubmed ID
Authors

Sung Ho Hwang, Yu-Whan Oh, Dae In Lee, Jaemin Shim, Sang-Weon Park, Young-Hoon Kim

Abstract

The complex fractioned atrial electrogram (CFAE) has been considered as the catheter ablation target of left atrium (LA) under persistent atrial fibrillation (PeAF). We evaluated the relation between the LA wall composition by late gadolinium enhancement cardiac magnetic resonance (LGE-CMR) and the CFAE in patients with PeAF. Forty-three patients underwent LGE-CMR and CFAE mapping before catheter ablation for PeAF. The LA wall substrates were classified into three: the fibrotic, intermediate, and normal substrates by using two thresholds of 2 standard deviation (2-SD) and 6-SD above the mean signal from the normal myocardium. For each of 12 preselected LA wall regions, the composition ratios (CRs) of fibrotic, indeterminate, and normal substrates were calculated as a percentage to the volume of LA wall region, and compared depending on the CFAE, respectively. The CR of normal substrate was significantly greater at the LA wall region with CFAE (52 ± 38 % vs. 20 ± 28 %, P < 0.01) than without CFAE. In contrast, the LA wall region with CFAE showed significantly lower CRs of intermediate substrate (39 ± 34 % vs. 57 ± 31 %, P < 0.01) and fibrotic substrate (7 ± 17 % vs. 21 ± 24 %, P < 0.01) than did the LA wall region without CFAE, respectively. Thus, the high CR (>18 %) of normal substrate predicted the CFAE at the corresponding LA wall region with 71 % sensitivity and 62 % specificity. In conclusion, the evaluation of LA wall normal substrate by LGE-CMR might be useful to predict the CFAE occurrence before catheter ablation of PeAF.

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X Demographics

The data shown below were collected from the profiles of 3 X users who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 20 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Unknown 20 100%

Demographic breakdown

Readers by professional status Count As %
Student > Master 3 15%
Researcher 2 10%
Other 1 5%
Lecturer 1 5%
Student > Ph. D. Student 1 5%
Other 3 15%
Unknown 9 45%
Readers by discipline Count As %
Medicine and Dentistry 7 35%
Engineering 2 10%
Computer Science 1 5%
Nursing and Health Professions 1 5%
Unknown 9 45%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 2. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 11 May 2015.
All research outputs
#16,722,190
of 25,374,917 outputs
Outputs from The International Journal of Cardiovascular Imaging
#802
of 2,012 outputs
Outputs of similar age
#159,147
of 278,621 outputs
Outputs of similar age from The International Journal of Cardiovascular Imaging
#12
of 35 outputs
Altmetric has tracked 25,374,917 research outputs across all sources so far. This one is in the 32nd percentile – i.e., 32% of other outputs scored the same or lower than it.
So far Altmetric has tracked 2,012 research outputs from this source. They receive a mean Attention Score of 2.3. This one has gotten more attention than average, scoring higher than 54% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 278,621 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 39th percentile – i.e., 39% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 35 others from the same source and published within six weeks on either side of this one. This one has gotten more attention than average, scoring higher than 62% of its contemporaries.