You are seeing a free-to-access but limited selection of the activity Altmetric has collected about this research output.
Click here to find out more.
Mendeley readers
Attention Score in Context
| Title |
The Evolutionary History of Prosaposin: Two Successive Tandem-Duplication Events Gave Rise to the Four Saposin Domains in Vertebrates
|
|---|---|
| Published in |
Journal of Molecular Evolution, January 2002
|
| DOI | 10.1007/s00239-001-0014-0 |
| Pubmed ID | |
| Authors |
Einat Hazkani-Covo, Neta Altman, Mia Horowitz, Dan Graur |
| Abstract |
Prosaposin is a multifunctional protein encoded by a single-copy gene. It contains four saposin domains (A, B, C, and D) occurring as tandem repeats connected by linker sequences. Because the saposin domains are similar to one another, it is deduced that they were created by sequential duplications of an ancestral domain. There are two types of evolutionary scenarios that may explain the creation of the four-domain gene: (1) two rounds of tandem internal gene duplication and (2) three rounds of duplications. An evolutionary and phylogenetic analysis of saposin DNA and amino acid sequences from human, mouse, rat, chicken, and zebrafish indicates that the first evolutionary scenario is the most likely. Accordingly, an ancestral saposin-unit duplication produced a two-domain gene, which, subsequently, underwent a second complete tandem duplication to give rise to the present four-domain structure of the prosaposin gene. |
Mendeley readers
The data shown below were compiled from readership statistics for 44 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| United States | 2 | 5% |
| Mexico | 1 | 2% |
| Argentina | 1 | 2% |
| Unknown | 40 | 91% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Student > Ph. D. Student | 11 | 25% |
| Researcher | 8 | 18% |
| Student > Postgraduate | 7 | 16% |
| Student > Bachelor | 5 | 11% |
| Professor > Associate Professor | 4 | 9% |
| Other | 7 | 16% |
| Unknown | 2 | 5% |
| Readers by discipline | Count | As % |
|---|---|---|
| Agricultural and Biological Sciences | 26 | 59% |
| Biochemistry, Genetics and Molecular Biology | 7 | 16% |
| Environmental Science | 3 | 7% |
| Chemistry | 2 | 5% |
| Veterinary Science and Veterinary Medicine | 1 | 2% |
| Other | 3 | 7% |
| Unknown | 2 | 5% |
Attention Score in Context
This research output has an Altmetric Attention Score of 3. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 29 March 2012.
All research outputs
#8,535,472
of 25,374,647 outputs
Outputs from Journal of Molecular Evolution
#493
of 1,477 outputs
Outputs of similar age
#32,445
of 130,776 outputs
Outputs of similar age from Journal of Molecular Evolution
#4
of 5 outputs
Altmetric has tracked 25,374,647 research outputs across all sources so far. This one is in the 43rd percentile – i.e., 43% of other outputs scored the same or lower than it.
So far Altmetric has tracked 1,477 research outputs from this source. They typically receive a little more attention than average, with a mean Attention Score of 5.9. This one is in the 29th percentile – i.e., 29% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 130,776 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 16th percentile – i.e., 16% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 5 others from the same source and published within six weeks on either side of this one.