Title |
Imidapril
|
---|---|
Published in |
Drugs, September 2012
|
DOI | 10.2165/00003495-200767090-00008 |
Pubmed ID | |
Authors |
Dean M. Robinson, Monique P. Curran, Katherine A. Lyseng-Williamson |
Abstract |
Imidapril (Tanatril), through its active metabolite imidaprilat, acts as an ACE inhibitor to suppress the conversion of angiotensin I to angiotensin II and thereby reduce total peripheral resistance and systemic blood pressure (BP). In clinical trials, oral imidapril was an effective antihypertensive agent in the treatment of mild to moderate essential hypertension. Some evidence suggests that imidapril also improves exercise capacity in patients with chronic heart failure (CHF) and reduces urinary albumin excretion rate in patients with type 1 diabetes mellitus. Imidapril was well tolerated, with a lower incidence of dry cough than enalapril or benazepril, and is a first choice ACE inhibitor for the treatment of mild to moderate essential hypertension. |
Mendeley readers
Geographical breakdown
Country | Count | As % |
---|---|---|
Unknown | 38 | 100% |
Demographic breakdown
Readers by professional status | Count | As % |
---|---|---|
Student > Ph. D. Student | 7 | 18% |
Student > Bachelor | 7 | 18% |
Researcher | 4 | 11% |
Student > Master | 3 | 8% |
Student > Doctoral Student | 2 | 5% |
Other | 5 | 13% |
Unknown | 10 | 26% |
Readers by discipline | Count | As % |
---|---|---|
Medicine and Dentistry | 15 | 39% |
Nursing and Health Professions | 3 | 8% |
Chemistry | 2 | 5% |
Sports and Recreations | 2 | 5% |
Agricultural and Biological Sciences | 1 | 3% |
Other | 5 | 13% |
Unknown | 10 | 26% |