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Tandem Repeats in Genes, Proteins, and Disease

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Cover of 'Tandem Repeats in Genes, Proteins, and Disease'

Table of Contents

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    Book Overview
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    Chapter 1 Longitudinal Imaging and Analysis of Neurons Expressing Polyglutamine-Expanded Proteins
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    Chapter 2 Atomic Force Microscopy Assays for Evaluating Polyglutamine Aggregation in Solution and on Surfaces
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    Chapter 3 Morphometric Analysis of Huntington's Disease Neurodegeneration in Drosophila.
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    Chapter 4 Size analysis of polyglutamine protein aggregates using fluorescence detection in an analytical ultracentrifuge.
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    Chapter 5 A Method for the Incremental Expansion of Polyglutamine Repeats in Recombinant Proteins
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    Chapter 6 Tandem Repeats in Genes, Proteins, and Disease
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    Chapter 7 Characterizing social behavior in genetically targeted mouse models of brain disorders.
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    Chapter 8 PCR Amplification and Sequence Analysis of GC-Rich Sequences: Aristaless-Related Homeobox Example
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    Chapter 9 Challenges of “Sticky” Co-immunoprecipitation: Polyalanine Tract Protein–Protein Interactions
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    Chapter 10 Molecular Pathology of Polyalanine Expansion Disorders: New Perspectives from Mouse Models
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    Chapter 11 Yeast as a platform to explore polyglutamine toxicity and aggregation.
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    Chapter 12 Immuno-based Detection Assays to Quantify Distinct Mutant Huntingtin Conformations in Biological Samples.
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    Chapter 13 Modeling and Analysis of Repeat RNA Toxicity in Drosophila
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    Chapter 14 Analyzing Modifiers of Protein Aggregation in C. elegans by Native Agarose Gel Electrophoresis.
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    Chapter 15 Kinetic Analysis of Aggregation Data
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    Chapter 16 Tandem Repeats in Genes, Proteins, and Disease
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    Chapter 17 Detecting Soluble PolyQ Oligomers and Investigating Their Impact on Living Cells Using Split-GFP
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    Chapter 18 Cell Biological Approaches to Investigate Polyglutamine-Expanded AR Metabolism
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