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Exacerbated symptoms in Blastocystis sp.-infected patients treated with metronidazole: two case studies

Overview of attention for article published in Parasitology Research, June 2018
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Title
Exacerbated symptoms in Blastocystis sp.-infected patients treated with metronidazole: two case studies
Published in
Parasitology Research, June 2018
DOI 10.1007/s00436-018-5948-x
Pubmed ID
Authors

Arutchelvan Rajamanikam, Suresh Kumar, Chandramathi Samudi, Madhav Kudva

Abstract

Blastocystis sp. is a gastrointestinal (GI) protozoan parasite reported to cause non-specific GI symptoms including diarrhea, flatulence, abdominal pain, and nausea. Complete eradication of Blastocystis sp. is rather challenging even with the drug of choice, i.e., metronidazole. Here, we report on two Blastocystis sp.-infected individuals, who presented increased parasite load and exacerbated symptoms upon treatment with the usual recommended dosage and regime of metronidazole. The two studies uniquely demonstrate for the first time a cyst count as high as fivefold more than the original cyst count before treatment and show an exacerbation of GI symptoms despite treatment. The study provides additional support in recognizing metronidazole resistance in Blastocystis sp. and its consequences towards the pathogenicity of the parasite.

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The data shown below were collected from the profile of 1 X user who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 22 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Unknown 22 100%

Demographic breakdown

Readers by professional status Count As %
Researcher 4 18%
Student > Master 3 14%
Student > Bachelor 2 9%
Student > Doctoral Student 1 5%
Student > Ph. D. Student 1 5%
Other 3 14%
Unknown 8 36%
Readers by discipline Count As %
Medicine and Dentistry 8 36%
Nursing and Health Professions 2 9%
Agricultural and Biological Sciences 2 9%
Biochemistry, Genetics and Molecular Biology 1 5%
Veterinary Science and Veterinary Medicine 1 5%
Other 1 5%
Unknown 7 32%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 21 April 2019.
All research outputs
#20,520,426
of 23,088,369 outputs
Outputs from Parasitology Research
#2,899
of 3,802 outputs
Outputs of similar age
#289,334
of 329,782 outputs
Outputs of similar age from Parasitology Research
#79
of 115 outputs
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So far Altmetric has tracked 3,802 research outputs from this source. They receive a mean Attention Score of 2.7. This one is in the 1st percentile – i.e., 1% of its peers scored the same or lower than it.
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We're also able to compare this research output to 115 others from the same source and published within six weeks on either side of this one. This one is in the 1st percentile – i.e., 1% of its contemporaries scored the same or lower than it.