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A Novel Technique for Repositioning of a Migrated ILUVIEN® (Fluocinolone Acetonide) Implant into the Anterior Chamber

Overview of attention for article published in Ophthalmology and Therapy, July 2015
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Title
A Novel Technique for Repositioning of a Migrated ILUVIEN® (Fluocinolone Acetonide) Implant into the Anterior Chamber
Published in
Ophthalmology and Therapy, July 2015
DOI 10.1007/s40123-015-0035-1
Pubmed ID
Authors

Ibraheem A. El-Ghrably, Ahmed Saad, Christiana Dinah

Abstract

Fluocinolone acetonide (FAc) intravitreal implant (ILUVIEN(®); Alimera Sciences Limited, Aldershot, UK) has been approved in the UK for the treatment of chronic diabetic macula edema, insufficiently responsive to available therapies. It is inserted into the vitreous cavity through a 25-gauge needle. Migration of the implant to the anterior chamber (AC) can occur through gaps in the posterior capsule especially in vitrectomized eyes. Early removal of AC-dislocated FAc implant is essential to prevent corneal edema and damage from raised intraocular pressure. To demonstrate a simple and novel technique, with a previous capsular tear, for removal of AC-migrated FAc implant and reinsertion into the vitreous cavity without compromising implant integrity. A side port incision was created with a keratome and an anterior chamber maintainer introduced and secured. Subsequently, a corneal incision was created at 12 o'clock through which a 23-gauge backflush needle (flute needle) was advanced into the anterior chamber and passive suction used to secure the implant. The flute needle was then placed through the defect in the posterior capsule and the exit port blocked, causing loss of suction and allowing the implant to fall into the posterior segment. The sulcus intraocular lens (IOL) was centralized simply by manipulating it approximately 180 degrees to provide adequate anterior capsule support. The FAc implant was successfully removed from AC in two patients and reinserted into the vitreous cavity without damage or complications either for the eye or the implant. IOL in both patients were repositioned to close the gap in posterior capsule. After 2 months, the implant remains in the vitreous cavity. This paper presents data from one of these cases. Using 23-gauge flute needle to retrieve dislocated FAc implant is a safe and easy technique. Alimera Sciences Ltd.

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Mendeley readers

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The data shown below were compiled from readership statistics for 23 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Unknown 23 100%

Demographic breakdown

Readers by professional status Count As %
Other 10 43%
Student > Master 3 13%
Student > Doctoral Student 2 9%
Student > Bachelor 1 4%
Researcher 1 4%
Other 0 0%
Unknown 6 26%
Readers by discipline Count As %
Pharmacology, Toxicology and Pharmaceutical Science 5 22%
Medicine and Dentistry 4 17%
Biochemistry, Genetics and Molecular Biology 3 13%
Nursing and Health Professions 2 9%
Chemical Engineering 1 4%
Other 2 9%
Unknown 6 26%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 05 August 2015.
All research outputs
#20,284,384
of 22,818,766 outputs
Outputs from Ophthalmology and Therapy
#557
of 568 outputs
Outputs of similar age
#220,509
of 263,982 outputs
Outputs of similar age from Ophthalmology and Therapy
#4
of 4 outputs
Altmetric has tracked 22,818,766 research outputs across all sources so far. This one is in the 1st percentile – i.e., 1% of other outputs scored the same or lower than it.
So far Altmetric has tracked 568 research outputs from this source. They typically receive a little more attention than average, with a mean Attention Score of 6.0. This one is in the 1st percentile – i.e., 1% of its peers scored the same or lower than it.
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