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Coaxial Electrospray Ionization for the Study of Rapid In-source Chemistry

Overview of attention for article published in Journal of the American Society for Mass Spectrometry, June 2018
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Title
Coaxial Electrospray Ionization for the Study of Rapid In-source Chemistry
Published in
Journal of the American Society for Mass Spectrometry, June 2018
DOI 10.1007/s13361-018-2004-0
Pubmed ID
Authors

Brynn N. Sundberg, Anthony F. Lagalante

Abstract

Coaxial electrospray has been used effectively for several dual-emitter applications, but has not been utilized for the study of rapid in-source chemistry. In this paper, we report the fabrication of a coaxial, micro-volume dual-emitter through the modification of a manufacturer's standard electrospray probe. This modification creates rapid mixing inside the Taylor cone and the ability to manipulate fast reactions using a variety of solvents and analytes. We demonstrate its potential as a low-cost, dual-emitter assembly for diverse applications through three examples: relative ionization in a biphasic electrospray, hydrogen-deuterium exchange, and protein supercharging. Graphical Abstract.

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Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 16 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Unknown 16 100%

Demographic breakdown

Readers by professional status Count As %
Student > Master 3 19%
Unspecified 2 13%
Professor 2 13%
Researcher 2 13%
Student > Ph. D. Student 2 13%
Other 1 6%
Unknown 4 25%
Readers by discipline Count As %
Chemistry 5 31%
Engineering 3 19%
Unspecified 2 13%
Earth and Planetary Sciences 1 6%
Biochemistry, Genetics and Molecular Biology 1 6%
Other 0 0%
Unknown 4 25%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 18 September 2018.
All research outputs
#20,663,600
of 25,382,440 outputs
Outputs from Journal of the American Society for Mass Spectrometry
#3,086
of 3,835 outputs
Outputs of similar age
#266,037
of 341,533 outputs
Outputs of similar age from Journal of the American Society for Mass Spectrometry
#53
of 74 outputs
Altmetric has tracked 25,382,440 research outputs across all sources so far. This one is in the 10th percentile – i.e., 10% of other outputs scored the same or lower than it.
So far Altmetric has tracked 3,835 research outputs from this source. They receive a mean Attention Score of 3.8. This one is in the 10th percentile – i.e., 10% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 341,533 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 12th percentile – i.e., 12% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 74 others from the same source and published within six weeks on either side of this one. This one is in the 4th percentile – i.e., 4% of its contemporaries scored the same or lower than it.