MACROD2 Haploinsufficiency Impairs Catalytic Activity of PARP1 and Promotes Chromosome Instability and Growth of Intestinal Tumors

Overview of attention for article published in Cancer Discovery, August 2018

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#Report on MACROD2 #haploinsufficiency, Colon #cancer and #PARP1 #enzymatic inactivation which Promotes Chromosome Instability. More #data in #proof of #concept should, and will, be available, #soon #enough!. ÁGORA, #expert #PARPologist is #Lindauforlife.

RT @AACR: Recently released in Cancer Discovery, Loss of the mono-ADP-ribosylhydrolase MACROD2 suppresses PARP1 activity to induce chromoso…

RT @AACR: Recently released in Cancer Discovery, Loss of the mono-ADP-ribosylhydrolase MACROD2 suppresses PARP1 activity to induce chromoso…

RT @AACR: Recently released in Cancer Discovery, Loss of the mono-ADP-ribosylhydrolase MACROD2 suppresses PARP1 activity to induce chromoso…

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