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The incidence, prevalence, and survival of systemic sclerosis in the UK Clinical Practice Research Datalink

Overview of attention for article published in Clinical Rheumatology, June 2018
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  • In the top 25% of all research outputs scored by Altmetric
  • High Attention Score compared to outputs of the same age (90th percentile)
  • High Attention Score compared to outputs of the same age and source (97th percentile)

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Title
The incidence, prevalence, and survival of systemic sclerosis in the UK Clinical Practice Research Datalink
Published in
Clinical Rheumatology, June 2018
DOI 10.1007/s10067-018-4182-3
Pubmed ID
Authors

Jeremy G. Royle, Peter C. Lanyon, Matthew J. Grainge, Abhishek Abhishek, Fiona A. Pearce

Abstract

To estimate the incidence, prevalence, and survival of systemic sclerosis in the United Kingdom. We conducted a historical cohort study using data from the Clinical Practice Research Datalink (CPRD). We calculated the incidence and survival of systemic sclerosis between 1994 and 2013 and examined its association with age, sex, and socioeconomic status. We calculated point prevalence on 1 July 2013 and examined its association with the same exposures. We identified 1327 cases with incident systemic sclerosis. Annual incidence was 19.4 per million person-years between 1994 and 2013. The incidence was 4.7 times higher in women than in men, was not influenced by socioeconomic status, and has remained stable over the 20 year study period. The peak age of onset was 55-69 years. Survival at 1, 5, and 10 years was 94.2, 80.0, and 65.7%, respectively. The prevalence was 307 (290-323) per million with the highest prevalence in the 70-84 years age group. We estimate there are currently 1180 new cases of systemic sclerosis each year in the UK, and 19,390 people living with systemic sclerosis. Due to the predicted growth and aging of the population, we predict a 24% increase in incident cases and 26% increase in prevalent cases in 20 years' time. Our estimates of incidence and prevalence are higher than previously reported in the UK, but similar to recent USA and Swedish studies, and do not support a north-south gradient of the occurrence of systemic sclerosis in Europe.

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X Demographics

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Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 111 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Unknown 111 100%

Demographic breakdown

Readers by professional status Count As %
Student > Ph. D. Student 17 15%
Researcher 14 13%
Other 11 10%
Student > Bachelor 6 5%
Student > Postgraduate 6 5%
Other 21 19%
Unknown 36 32%
Readers by discipline Count As %
Medicine and Dentistry 30 27%
Pharmacology, Toxicology and Pharmaceutical Science 9 8%
Immunology and Microbiology 7 6%
Biochemistry, Genetics and Molecular Biology 6 5%
Nursing and Health Professions 5 5%
Other 12 11%
Unknown 42 38%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 23. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 29 November 2018.
All research outputs
#1,441,070
of 23,577,761 outputs
Outputs from Clinical Rheumatology
#125
of 3,091 outputs
Outputs of similar age
#32,296
of 329,623 outputs
Outputs of similar age from Clinical Rheumatology
#2
of 68 outputs
Altmetric has tracked 23,577,761 research outputs across all sources so far. Compared to these this one has done particularly well and is in the 93rd percentile: it's in the top 10% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 3,091 research outputs from this source. They typically receive a little more attention than average, with a mean Attention Score of 7.0. This one has done particularly well, scoring higher than 95% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 329,623 tracked outputs that were published within six weeks on either side of this one in any source. This one has done particularly well, scoring higher than 90% of its contemporaries.
We're also able to compare this research output to 68 others from the same source and published within six weeks on either side of this one. This one has done particularly well, scoring higher than 97% of its contemporaries.