4/9 As shown in Dr. @SadiaNajam et al. 2019, hyperphagia is one of the critical driving forces to induce #obesity upon Dicer deletion in mature forebrain neurons, while increasing leptin production could successfully normalize food intake, but not weight.
2/9 Melanocortin system comprises anorexigenic proopiomelanocortin (POMC) and orexigenic agouti-related protein neurons within the arcuate nucleus of the hypothalamus. They receive signals and project signals to other parts of adult🧠to maintain energy⚖️ h
RT @vinnikovLAB: As @SadiaNajam mentioned in https://t.co/9QrmhzzikY, hypothalamic microRNAs are critical for energy homeostasis control in…
As @SadiaNajam mentioned in https://t.co/9QrmhzzikY, hypothalamic microRNAs are critical for energy homeostasis control in the adulthood. The questions were: which ones exactly play the major role and in which neuronal population(s)? Now we have an answer