Title |
Virus‐triggered autophagy in viral hepatitis – possible novel strategies for drug development
|
---|---|
Published in |
Journal of Viral Hepatitis, October 2011
|
DOI | 10.1111/j.1365-2893.2011.01530.x |
Pubmed ID | |
Authors |
S. M. Alavian, S. R. Ande, K. M. Coombs, B. Yeganeh, P. Davoodpour, M. Hashemi, M. Los, S. Ghavami |
Abstract |
Autophagy is a very tightly regulated process that is important in many cellular processes including development, differentiation, survival and homoeostasis. The importance of this process has already been proven in numerous common diseases such as cancer and neurodegenerative disorders. Emerging data indicate that autophagy plays an important role in some liver diseases including liver injury induced by ischaemia reperfusion and alpha-1 antitrypsin Z allele-dependent liver disease. Autophagy may also occur in viral infection, and it may play a crucial role in antimicrobial host defence against pathogens, while supporting cellular homoeostasis processes. Here, the latest findings on the role of autophagy in viral hepatitis B and C infection, which are both serious health threats, will be reviewed. |
X Demographics
Geographical breakdown
Country | Count | As % |
---|---|---|
United States | 1 | 100% |
Demographic breakdown
Type | Count | As % |
---|---|---|
Members of the public | 1 | 100% |
Mendeley readers
Geographical breakdown
Country | Count | As % |
---|---|---|
Sri Lanka | 1 | 3% |
France | 1 | 3% |
Unknown | 31 | 94% |
Demographic breakdown
Readers by professional status | Count | As % |
---|---|---|
Student > Doctoral Student | 5 | 15% |
Professor | 4 | 12% |
Student > Ph. D. Student | 3 | 9% |
Researcher | 3 | 9% |
Student > Bachelor | 3 | 9% |
Other | 11 | 33% |
Unknown | 4 | 12% |
Readers by discipline | Count | As % |
---|---|---|
Agricultural and Biological Sciences | 7 | 21% |
Medicine and Dentistry | 5 | 15% |
Biochemistry, Genetics and Molecular Biology | 4 | 12% |
Nursing and Health Professions | 2 | 6% |
Engineering | 2 | 6% |
Other | 6 | 18% |
Unknown | 7 | 21% |