You are seeing a free-to-access but limited selection of the activity Altmetric has collected about this research output.
Click here to find out more.
X Demographics
Mendeley readers
Attention Score in Context
| Title |
Genome-wide association studies for multiple diseases of the German Shepherd Dog
|
|---|---|
| Published in |
Mammalian Genome, November 2011
|
| DOI | 10.1007/s00335-011-9376-9 |
| Pubmed ID | |
| Authors |
Kate L. Tsai, Rooksana E. Noorai, Alison N. Starr-Moss, Pascale Quignon, Caitlin J. Rinz, Elaine A. Ostrander, Jörg M. Steiner, Keith E. Murphy, Leigh Anne Clark |
| Abstract |
The German Shepherd Dog (GSD) is a popular working and companion breed for which over 50 hereditary diseases have been documented. Herein, SNP profiles for 197 GSDs were generated using the Affymetrix v2 canine SNP array for a genome-wide association study to identify loci associated with four diseases: pituitary dwarfism, degenerative myelopathy (DM), congenital megaesophagus (ME), and pancreatic acinar atrophy (PAA). A locus on Chr 9 is strongly associated with pituitary dwarfism and is proximal to a plausible candidate gene, LHX3. Results for DM confirm a major locus encompassing SOD1, in which an associated point mutation was previously identified, but do not suggest modifier loci. Several SNPs on Chr 12 are associated with ME and a 4.7 Mb haplotype block is present in affected dogs. Analysis of additional ME cases for a SNP within the haplotype provides further support for this association. Results for PAA indicate more complex genetic underpinnings. Several regions on multiple chromosomes reach genome-wide significance. However, no major locus is apparent and only two associated haplotype blocks, on Chrs 7 and 12 are observed. These data suggest that PAA may be governed by multiple loci with small effects, or it may be a heterogeneous disorder. |
X Demographics
The data shown below were collected from the profile of 1 X user who shared this research output. Click here to find out more about how the information was compiled.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Australia | 1 | 100% |
Demographic breakdown
| Type | Count | As % |
|---|---|---|
| Scientists | 1 | 100% |
Mendeley readers
The data shown below were compiled from readership statistics for 68 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| United States | 2 | 3% |
| Colombia | 1 | 1% |
| Unknown | 65 | 96% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Student > Ph. D. Student | 14 | 21% |
| Researcher | 11 | 16% |
| Other | 8 | 12% |
| Student > Bachelor | 7 | 10% |
| Student > Master | 7 | 10% |
| Other | 8 | 12% |
| Unknown | 13 | 19% |
| Readers by discipline | Count | As % |
|---|---|---|
| Agricultural and Biological Sciences | 27 | 40% |
| Veterinary Science and Veterinary Medicine | 9 | 13% |
| Biochemistry, Genetics and Molecular Biology | 6 | 9% |
| Medicine and Dentistry | 6 | 9% |
| Neuroscience | 2 | 3% |
| Other | 5 | 7% |
| Unknown | 13 | 19% |
Attention Score in Context
This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 16 February 2015.
All research outputs
#17,652,807
of 22,659,164 outputs
Outputs from Mammalian Genome
#977
of 1,123 outputs
Outputs of similar age
#191,297
of 239,425 outputs
Outputs of similar age from Mammalian Genome
#10
of 16 outputs
Altmetric has tracked 22,659,164 research outputs across all sources so far. This one is in the 19th percentile – i.e., 19% of other outputs scored the same or lower than it.
So far Altmetric has tracked 1,123 research outputs from this source. They receive a mean Attention Score of 4.6. This one is in the 10th percentile – i.e., 10% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 239,425 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 18th percentile – i.e., 18% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 16 others from the same source and published within six weeks on either side of this one. This one is in the 37th percentile – i.e., 37% of its contemporaries scored the same or lower than it.