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Chordoma: a systematic review of the epidemiology and clinical prognostic factors predicting progression-free and overall survival

Overview of attention for article published in European Spine Journal, September 2018
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Title
Chordoma: a systematic review of the epidemiology and clinical prognostic factors predicting progression-free and overall survival
Published in
European Spine Journal, September 2018
DOI 10.1007/s00586-018-5764-0
Pubmed ID
Authors

S. H. Bakker, W. C. H. Jacobs, W. Pondaag, H. Gelderblom, R. A. Nout, P. D. S. Dijkstra, W. C. Peul, C. L. A. Vleggeert-Lankamp

Abstract

The aim of this systematic review is to describe the epidemiology of chordoma and to provide a clear overview of clinical prognostic factors predicting progression-free and overall survival. Four databases of medical literature were searched. Separate searches were performed for each of the two objectives. Reference and citation tracking was performed. Papers were processed by two independent reviewers according to a protocol that included risk of bias analysis. Disagreement was resolved by discussion. Pooled analyses were planned if homogeneity of data would allow. Incidence-incidence rates ranged between 0.18 and 0.84 per million persons per year and varied between countries and presumably between races. On average patients were diagnosed in their late fifties and gender data indicate clear male predominance. Two of the largest studies (n = 400 and n = 544) reported different anatomical distributions: one reporting the skull base and sacrococcygeal area affected in 32% and 29% of cases, whereas the other reporting that they were affected in 26% and 45% of cases, respectively. Statistically significant adverse prognostic factors predicting progression-free and overall survival include female sex, older age, bigger tumour size, increasing extent of tumour invasion, non-total resection, presence of metastasis, local recurrence, and dedifferentiated histological subtype. Incidence rate and anatomical distribution vary between countries and presumably between races. Most chordomas arise in the skull base and sacrococcygeal spine, and the tumour shows clear male predominance. Multiple adverse prognostic factors predicting progression-free and overall survival were identified in subgroups of patients. These slides can be retrieved under Electronic Supplementary Material.

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The data shown below were collected from the profiles of 2 X users who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 82 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Unknown 82 100%

Demographic breakdown

Readers by professional status Count As %
Researcher 13 16%
Student > Postgraduate 8 10%
Other 7 9%
Student > Ph. D. Student 7 9%
Student > Doctoral Student 6 7%
Other 15 18%
Unknown 26 32%
Readers by discipline Count As %
Medicine and Dentistry 34 41%
Neuroscience 3 4%
Biochemistry, Genetics and Molecular Biology 3 4%
Unspecified 2 2%
Agricultural and Biological Sciences 2 2%
Other 8 10%
Unknown 30 37%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 2. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 07 July 2020.
All research outputs
#14,140,645
of 23,103,436 outputs
Outputs from European Spine Journal
#1,710
of 4,691 outputs
Outputs of similar age
#182,640
of 337,900 outputs
Outputs of similar age from European Spine Journal
#35
of 87 outputs
Altmetric has tracked 23,103,436 research outputs across all sources so far. This one is in the 37th percentile – i.e., 37% of other outputs scored the same or lower than it.
So far Altmetric has tracked 4,691 research outputs from this source. They receive a mean Attention Score of 4.1. This one has gotten more attention than average, scoring higher than 62% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 337,900 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 44th percentile – i.e., 44% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 87 others from the same source and published within six weeks on either side of this one. This one has gotten more attention than average, scoring higher than 57% of its contemporaries.