Bactericidal/Permeability-Increasing Fold-Containing Family B Member 4 May Be Associated with NSAID-Induced Enteropathy

NSAIDs are infrequently associated with enteropathy, Why only a small subset of NSAID users develop it is unknown. Fujimori et al report several polymorphisms in gene BPIFB4 were strongly associated with enteropathy. https://t.co/L0aLIpaGM9

A small # of NSAID users develop NSAID enteropathy. It may manifest as iron deficiency & vague abdominal pain. The authors use sophisticated genetic techniques to identify a population of NSAID users that have a high propensity to develop enteropathy.