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Kinase Screening and Profiling

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Cover of 'Kinase Screening and Profiling'

Table of Contents

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    Book Overview
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    Chapter 1 HTRF Kinase Assay Development and Methods in Inhibitor Characterization
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    Chapter 2 Application of Eukaryotic Elongation Factor-2 Kinase (eEF-2K) for Cancer Therapy: Expression, Purification, and High-Throughput Inhibitor Screening
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    Chapter 3 Recombinant Kinase Production and Fragment Screening by NMR Spectroscopy.
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    Chapter 4 Bioluminescence Methods for Assaying Kinases in Quantitative High-Throughput Screening (qHTS) Format Applied to Yes1 Tyrosine Kinase, Glucokinase, and PI5P4Kα Lipid Kinase
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    Chapter 5 Using Bioluminescent Kinase Profiling Strips to Identify Kinase Inhibitor Selectivity and Promiscuity
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    Chapter 6 Measuring Activity of Phosphoinositide Lipid Kinases Using a Bioluminescent ADP-Detecting Assay.
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    Chapter 7 A High-Throughput Radiometric Kinase Assay
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    Chapter 8 A High-Content Assay to Screen for Modulators of EGFR Function
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    Chapter 9 Monitoring Protein Kinase Expression and Phosphorylation in Cell Lysates with Antibody Microarrays
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    Chapter 10 From Enzyme to Whole Blood: Sequential Screening Procedure for Identification and Evaluation of p38 MAPK Inhibitors.
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    Chapter 11 Genetically Encoded Fluorescent Indicators to Visualize Protein Phosphorylation in Living Cells
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    Chapter 12 Characterization of an Engineered Src Kinase to Study Src Signaling and Biology
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    Chapter 13 Screening One-Bead-One-Compound Peptide Libraries for Optimal Kinase Substrates
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    Chapter 14 Determination of the Substrate Specificity of Protein Kinases with Peptide Micro- and Macroarrays
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    Chapter 15 Rapid Identification of Protein Kinase Phosphorylation Site Motifs Using Combinatorial Peptide Libraries
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