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Fragile-X Syndrome

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Cover of 'Fragile-X Syndrome'

Table of Contents

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    Book Overview
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    Chapter 1 Fragile X Syndrome: Introduction
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    Chapter 2 Clinical Genetic Testing for Fragile X Syndrome by Polymerase Chain Reaction Amplification and Southern Blot Analyses
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    Chapter 3 Monitoring for Epigenetic Modifications at the FMR1 Locus
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    Chapter 4 Assays for Determining Repeat Number, Methylation Status, and AGG Interruptions in the Fragile X-Related Disorders
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    Chapter 5 One-Step Generation of Seamless Luciferase Gene Knockin Using CRISPR/Cas9 Genome Editing in Human Pluripotent Stem Cells
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    Chapter 6 Modeling FXS with Mouse Neural Progenitors
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    Chapter 7 Using Human Neural Progenitor Cell Models to Conduct Large-Scale Drug Screens for Neurological and Psychiatric Diseases
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    Chapter 8 Modeling FXS: Human Pluripotent Stem Cells and In Vitro Neural Differentiation
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    Chapter 9 Induced Neurons for the Study of Neurodegenerative and Neurodevelopmental Disorders
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    Chapter 10 Imaging of Somatic Ca2+ Transients in Differentiated Human Neurons
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    Chapter 11 Patch-Clamp Recordings from Human Embryonic Stem Cells-Derived Fragile X Neurons
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    Chapter 12 Application of Drosophila Model Toward Understanding the Molecular Basis of Fragile X Syndrome
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    Chapter 13 Fragile X Syndrome Pre-Clinical Research: Comparing Mouse- and Human-Based Models
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    Chapter 14 Pathophysiology Mechanisms in Fragile-X Primary Ovarian Insufficiency
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    Chapter 15 Fragile X-Associated Tremor/Ataxia Syndrome (FXTAS)
Attention for Chapter 8: Modeling FXS: Human Pluripotent Stem Cells and In Vitro Neural Differentiation
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