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Micrographia induced by pallidal DBS for segmental dystonia: a subtle sign of hypokinesia?

Overview of attention for article published in Journal of Neural Transmission, January 2011
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Title
Micrographia induced by pallidal DBS for segmental dystonia: a subtle sign of hypokinesia?
Published in
Journal of Neural Transmission, January 2011
DOI 10.1007/s00702-010-0544-y
Pubmed ID
Authors

Christian Blahak, Hans-Holger Capelle, Hansjoerg Baezner, Thomas M. Kinfe, Michael G. Hennerici, Joachim K. Krauss

Abstract

Recently parkinsonism has been reported as a rare side effect of globus pallidus internus (GPi) deep brain stimulation (DBS) for dystonia. In the present systematic prospective study in 11 patients with segmental dystonia not affecting distal arm function, we could demonstrate significant changes in handwriting characterized by mild micrographia following GPi-DBS. We propose that this finding reflects GPi-DBS-induced disturbances of basal ganglia function in terms of a mild hypokinetic syndrome, as a result of outflow alterations in pallido-thalamo-cortical pathways.

Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 36 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
United States 1 3%
Netherlands 1 3%
Italy 1 3%
Unknown 33 92%

Demographic breakdown

Readers by professional status Count As %
Student > Ph. D. Student 5 14%
Other 4 11%
Researcher 4 11%
Student > Master 3 8%
Student > Bachelor 2 6%
Other 4 11%
Unknown 14 39%
Readers by discipline Count As %
Medicine and Dentistry 10 28%
Neuroscience 7 19%
Linguistics 1 3%
Social Sciences 1 3%
Nursing and Health Professions 1 3%
Other 2 6%
Unknown 14 39%