Title |
The impact of oral contraceptives on cardiometabolic parameters
|
---|---|
Published in |
Journal of Endocrinological Investigation, July 2015
|
DOI | 10.1007/s40618-015-0346-z |
Pubmed ID | |
Authors |
M. Farahmand, F. Ramezani Tehrani, M. Rostami Dovom, S. Hashemi, F. Azizi |
Abstract |
There is much controversy regarding the use of oral contraceptive pills (OCPs) on cardiometabolic parameters, which is why this longitudinal population-based study was conducted to assess the impact of OCP use and its duration on cardiometabolic factors. Of 5532 reproductive-aged participants of the Tehran lipid and glucose study, 3160 women who met our inclusion criteria were subdivided according to the duration of OCPs consumption into four sub-groups: (1) Non-users; (2) <11 month users; (3) 12-35 month users, and (4) ≥36 month users, and their cardiometabolic parameters were compared. No statistical significant differences were observed between the cardiometabolic parameters of these sub-groups, after further adjustment for confounding factors including age, parity, and education, except for mean low-density lipoprotein-cholesterol which was significantly higher in women who used OCPs for >36 months in comparison to non-OCP users. The odds ratio of hypercholesterolemia was significantly higher in women who used OCPs for >36 months in comparison to non-OCP users; being 1.5 times higher than non-users (95 % CI 1.01-2.2). Results showed that if used for less than 3 years, OCPs have no cardiometabolic effects. |
Mendeley readers
Geographical breakdown
Country | Count | As % |
---|---|---|
Unknown | 47 | 100% |
Demographic breakdown
Readers by professional status | Count | As % |
---|---|---|
Student > Master | 10 | 21% |
Student > Bachelor | 7 | 15% |
Researcher | 5 | 11% |
Professor | 3 | 6% |
Other | 3 | 6% |
Other | 8 | 17% |
Unknown | 11 | 23% |
Readers by discipline | Count | As % |
---|---|---|
Medicine and Dentistry | 14 | 30% |
Biochemistry, Genetics and Molecular Biology | 6 | 13% |
Nursing and Health Professions | 2 | 4% |
Agricultural and Biological Sciences | 2 | 4% |
Computer Science | 2 | 4% |
Other | 8 | 17% |
Unknown | 13 | 28% |