@solomonroubicek Beru zpět, tu je to: https://t.co/780rVqgnUg
.@davidasinclair is well aware that NMN doesn’t get into cells & that when you make it cell permeant, it kills them. this turned the value of the metro NMN analogs to zero. by the way, this activity of SARM1 is widely known https://t.co/GmykWfcglE
@MikeCruise18 @davidasinclair someone can ask him since he thinks NMN gets into cells intact, how he explains the cell death caused by such compounds & if he’s still developing modified NMN https://t.co/GmykWfcglE
@VishalBirar No, by masking NMN you would no longer need NMRK1. problem is by delivering NMN, you will activate SARM1 and cause neurotoxicity https://t.co/EFqq4EMuKU this is why Metro Biotech is stuck with crystalline NMN. MIB626 will just deliver NR &