The Relationship Between Polygenic Risk Scores and Cognition in Schizophrenia

@Beesalbob @RichardHanania @PGCgenetics @OrchidInc https://t.co/hUftNbL2eG this other PGC paper shows a negative correlation between schizophrenia and IQ -- having a high schizophrenia GRS makes you stupider, not smarter.

@anshulkundaje @sbmontgom @ShaiCarmi One caveat -- not sure it's being oversold with no harm. If it's not already happening, someone is going to sell a PRS for 'intelligence', which might possible increase the risk for schizophrenia: https://t.co/BgX99Od7

@adapkepinska Hi! This is *within* schizophrenia but looking specifically at cognition, don't know if it might be useful: https://t.co/pbMUDWhrjq (sadly Alex Richards not on Twitter yet!)

Interesting. Cognition in schizophrenia is more strongly associated with polygenic risk scores that index cognitive traits in the general population than polygenic risk scores for neuropsychiatric disorders. https://t.co/ECTufZEoAJ