A pharmacokinetic-pharmacodynamic assessment of oral antibiotics for pyelonephritis

Overview of attention for article published in European Journal of Clinical Microbiology & Infectious Diseases, September 2019

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@ConanMacDougall @BBookstaver_USC @JakeJohnsonMD @PaulSaxMD https://t.co/0RIBJ1zRFh

16 Aug 2020

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PK/PD simulation of oral beta-lactam for EUCAST-susceptible E.coli pyelonephritis looks pretty bleak- to achieve cumulative fractional response of 90% would require 7.5g amoxicillin/day, 16g cephalexin/day. OTOH, cipro achieved CFR >0.9 @ just 200mg q1

24 Oct 2019

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PUBLICATION: A pharmacokinetic-pharmacodynamic assessment of oral antibiotics for pyelonephritis. Published in the European Journal of Clinical Microbiology & Infectious Diseases (Sep 2019): https://t.co/SZss9xhWi8 #antibacterialagents #pkpd #pharmaco

13 Sep 2019

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