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Liposarcoma: molecular targets and therapeutic implications

Overview of attention for article published in Cellular and Molecular Life Sciences, May 2016
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1 X user
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Citations

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34 Dimensions

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77 Mendeley
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Title
Liposarcoma: molecular targets and therapeutic implications
Published in
Cellular and Molecular Life Sciences, May 2016
DOI 10.1007/s00018-016-2266-2
Pubmed ID
Authors

Kate Lynn J. Bill, Lucia Casadei, Bethany C. Prudner, Hans Iwenofu, Anne M. Strohecker, Raphael E. Pollock

Abstract

Liposarcoma (LPS) is the most common soft tissue sarcoma and accounts for approximately 20 % of all adult sarcomas. Current treatment modalities (surgery, chemotherapy, and radiotherapy) all have limitations; therefore, molecularly driven studies are needed to improve the identification and increased understanding of genetic and epigenetic deregulations in LPS if we are to successfully target specific tumorigenic drivers. It can be anticipated that such biology-driven therapeutics will improve treatments by selectively deleting cancer cells while sparing normal tissues. This review will focus on several therapeutically actionable molecular markers identified in well-differentiated LPS and dedifferentiated LPS, highlighting their potential clinical applicability.

X Demographics

X Demographics

The data shown below were collected from the profile of 1 X user who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 77 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
United States 1 1%
Unknown 76 99%

Demographic breakdown

Readers by professional status Count As %
Student > Postgraduate 27 35%
Student > Ph. D. Student 11 14%
Student > Bachelor 10 13%
Researcher 4 5%
Student > Master 4 5%
Other 8 10%
Unknown 13 17%
Readers by discipline Count As %
Biochemistry, Genetics and Molecular Biology 35 45%
Agricultural and Biological Sciences 12 16%
Medicine and Dentistry 11 14%
Engineering 2 3%
Pharmacology, Toxicology and Pharmaceutical Science 1 1%
Other 1 1%
Unknown 15 19%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 2. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 15 December 2016.
All research outputs
#15,492,086
of 23,794,258 outputs
Outputs from Cellular and Molecular Life Sciences
#2,969
of 4,151 outputs
Outputs of similar age
#183,299
of 313,843 outputs
Outputs of similar age from Cellular and Molecular Life Sciences
#58
of 86 outputs
Altmetric has tracked 23,794,258 research outputs across all sources so far. This one is in the 32nd percentile – i.e., 32% of other outputs scored the same or lower than it.
So far Altmetric has tracked 4,151 research outputs from this source. They typically receive a little more attention than average, with a mean Attention Score of 6.0. This one is in the 26th percentile – i.e., 26% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 313,843 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 38th percentile – i.e., 38% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 86 others from the same source and published within six weeks on either side of this one. This one is in the 30th percentile – i.e., 30% of its contemporaries scored the same or lower than it.