Title |
Effects of Chronic Dietary Selenomethionine Exposure on the Visual System of Adult and F1 Generation Zebrafish (Danio rerio)
|
---|---|
Published in |
Bulletin of Environmental Contamination and Toxicology, June 2016
|
DOI | 10.1007/s00128-016-1849-9 |
Pubmed ID | |
Authors |
Jason C. Raine, Lise Lallemand, Connor M. Pettem, David M. Janz |
Abstract |
The effects of chronic dietary selenomethionine (SeMet) exposure on the visual system of adult zebrafish and their progeny were investigated. Adult zebrafish were exposed to measured concentrations of 1.1 (control) and 10.3 µg Se/g dry mass as SeMet for 57 days, then encouraged to breed. Progeny were reared to swim-up and differences in mortality, eye size and visual behaviour were determined. Adult vision was also investigated using behavioural assays. Adults fed the SeMet-spiked diet exhibited significantly fewer positive reactions in the escape response assay when compared to controls. Larvae from adults fed elevated SeMet had smaller eyes and a lower proportion of positive responses in phototaxis, oculomotor and optokinetic response assays compared to controls. These results demonstrate that environmentally relevant elevated dietary SeMet exposure can affect the visual system of both exposed adult zebrafish and their progeny, which could affect fitness and survivability. |
X Demographics
Geographical breakdown
Country | Count | As % |
---|---|---|
Unknown | 1 | 100% |
Demographic breakdown
Type | Count | As % |
---|---|---|
Members of the public | 1 | 100% |
Mendeley readers
Geographical breakdown
Country | Count | As % |
---|---|---|
Unknown | 30 | 100% |
Demographic breakdown
Readers by professional status | Count | As % |
---|---|---|
Student > Bachelor | 5 | 17% |
Student > Ph. D. Student | 5 | 17% |
Researcher | 4 | 13% |
Student > Master | 3 | 10% |
Student > Doctoral Student | 2 | 7% |
Other | 3 | 10% |
Unknown | 8 | 27% |
Readers by discipline | Count | As % |
---|---|---|
Agricultural and Biological Sciences | 5 | 17% |
Environmental Science | 5 | 17% |
Pharmacology, Toxicology and Pharmaceutical Science | 3 | 10% |
Biochemistry, Genetics and Molecular Biology | 3 | 10% |
Sports and Recreations | 2 | 7% |
Other | 4 | 13% |
Unknown | 8 | 27% |