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What’s New in Regenerative Medicine: Split up of the Mesenchymal Stem Cell Family Promises New Hope for Cardiovascular Repair

Overview of attention for article published in Journal of Cardiovascular Translational Research, August 2012
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Title
What’s New in Regenerative Medicine: Split up of the Mesenchymal Stem Cell Family Promises New Hope for Cardiovascular Repair
Published in
Journal of Cardiovascular Translational Research, August 2012
DOI 10.1007/s12265-012-9395-2
Pubmed ID
Authors

Rosa Vono, Gaia Spinetti, Miriam Gubernator, Paolo Madeddu

Abstract

Coronary artery disease (CAD) is exceedingly prevalent and requires care optimization. Regenerative medicine holds promise to improve the clinical outcome of CAD patients. Current approach consists in subsidizing the infarcted heart with boluses of autologous stem cells from the bone marrow. Moreover, mesenchymal stem cells (MSCs) are in the focus of intense research owing to an apparent superiority in plasticity and regenerative capacity compared with hematopoietic stem cells. In this review, we report recent findings indicating the presence, within the heterogeneous MSC population, of perivascular stem cells expressing typical pericyte markers. Moreover, we focus on recent research showing the presence of similar cells in the adventitia of large vessels. These discoveries were fundamental to shape a roadmap toward clinical application in patients with myocardial ischemia. Adventitial stem cells are ideal candidates for promotion of cardiac repair owing to their ease of accessibility and expandability and potent vasculogenic activity.

X Demographics

X Demographics

The data shown below were collected from the profiles of 2 X users who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 35 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Italy 1 3%
Germany 1 3%
Brazil 1 3%
Unknown 32 91%

Demographic breakdown

Readers by professional status Count As %
Student > Ph. D. Student 10 29%
Student > Bachelor 6 17%
Researcher 4 11%
Student > Master 3 9%
Lecturer 2 6%
Other 7 20%
Unknown 3 9%
Readers by discipline Count As %
Medicine and Dentistry 12 34%
Agricultural and Biological Sciences 7 20%
Biochemistry, Genetics and Molecular Biology 5 14%
Engineering 2 6%
Pharmacology, Toxicology and Pharmaceutical Science 1 3%
Other 2 6%
Unknown 6 17%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 20 August 2012.
All research outputs
#15,249,959
of 22,675,759 outputs
Outputs from Journal of Cardiovascular Translational Research
#354
of 574 outputs
Outputs of similar age
#106,708
of 167,520 outputs
Outputs of similar age from Journal of Cardiovascular Translational Research
#9
of 10 outputs
Altmetric has tracked 22,675,759 research outputs across all sources so far. This one is in the 22nd percentile – i.e., 22% of other outputs scored the same or lower than it.
So far Altmetric has tracked 574 research outputs from this source. They typically receive a little more attention than average, with a mean Attention Score of 5.4. This one is in the 27th percentile – i.e., 27% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 167,520 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 26th percentile – i.e., 26% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 10 others from the same source and published within six weeks on either side of this one.