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Inhibition of cytosolic Phospholipase A2prevents prion peptide-induced neuronal damage and co-localisation with Beta III Tubulin

Overview of attention for article published in BMC Neuroscience, August 2012
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Title
Inhibition of cytosolic Phospholipase A2prevents prion peptide-induced neuronal damage and co-localisation with Beta III Tubulin
Published in
BMC Neuroscience, August 2012
DOI 10.1186/1471-2202-13-106
Pubmed ID
Authors

Victoria Last, Alun Williams, Dirk Werling

Abstract

Activation of phospholipase A2 (PLA2) and the subsequent metabolism of arachidonic acid (AA) to prostaglandins have been shown to play an important role in neuronal death in neurodegenerative disease. Here we report the effects of the prion peptide fragment HuPrP106-126 on the PLA2 cascade in primary cortical neurons and translocation of cPLA2 to neurites.

X Demographics

X Demographics

The data shown below were collected from the profile of 1 X user who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 40 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
France 1 3%
Germany 1 3%
Unknown 38 95%

Demographic breakdown

Readers by professional status Count As %
Researcher 10 25%
Student > Master 7 18%
Student > Bachelor 6 15%
Student > Ph. D. Student 5 13%
Student > Doctoral Student 2 5%
Other 4 10%
Unknown 6 15%
Readers by discipline Count As %
Biochemistry, Genetics and Molecular Biology 10 25%
Agricultural and Biological Sciences 10 25%
Chemistry 3 8%
Medicine and Dentistry 2 5%
Neuroscience 2 5%
Other 5 13%
Unknown 8 20%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 28 August 2012.
All research outputs
#18,313,878
of 22,675,759 outputs
Outputs from BMC Neuroscience
#878
of 1,240 outputs
Outputs of similar age
#130,374
of 170,196 outputs
Outputs of similar age from BMC Neuroscience
#24
of 38 outputs
Altmetric has tracked 22,675,759 research outputs across all sources so far. This one is in the 11th percentile – i.e., 11% of other outputs scored the same or lower than it.
So far Altmetric has tracked 1,240 research outputs from this source. They receive a mean Attention Score of 4.3. This one is in the 15th percentile – i.e., 15% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 170,196 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 10th percentile – i.e., 10% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 38 others from the same source and published within six weeks on either side of this one. This one is in the 15th percentile – i.e., 15% of its contemporaries scored the same or lower than it.