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Effect of eccentric training on mitochondrial function and oxidative stress in the skeletal muscle of rats

Overview of attention for article published in Brazilian Journal of Medical and Biological Research, January 2013
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37 Mendeley
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Title
Effect of eccentric training on mitochondrial function and oxidative stress in the skeletal muscle of rats
Published in
Brazilian Journal of Medical and Biological Research, January 2013
DOI 10.1590/1414-431x20121956
Pubmed ID
Authors

L.A. Silva, K.F. Bom, C.B. Tromm, G.L. Rosa, I. Mariano, B.G. Pozzi, T. Tuon, E.L. Stresck, C.T. Souza, R.A. Pinho

Abstract

The objective of the present study was to investigate the effects of eccentric training on the activity of mitochondrial respiratory chain enzymes, oxidative stress, muscle damage, and inflammation of skeletal muscle. Eighteen male mice (CF1) weighing 30-35 g were randomly divided into 3 groups (N = 6): untrained, trained eccentric running (16°; TER), and trained running (0°) (TR), and were submitted to an 8-week training program. TER increased muscle oxidative capacity (succinate dehydrogenase and complexes I and II) in a manner similar to TR, and TER did not decrease oxidative damage (xylenol and creatine phosphate) but increased antioxidant enzyme activity (superoxide dismutase and catalase) similar to TR. Muscle damage (creatine kinase) and inflammation (myeloperoxidase) were not reduced by TER. In conclusion, we suggest that TER improves mitochondrial function but does not reduce oxidative stress, muscle damage, or inflammation induced by eccentric contractions.

X Demographics

X Demographics

The data shown below were collected from the profiles of 3 X users who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 37 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Spain 1 3%
Brazil 1 3%
Unknown 35 95%

Demographic breakdown

Readers by professional status Count As %
Student > Master 7 19%
Student > Bachelor 5 14%
Professor 4 11%
Student > Ph. D. Student 4 11%
Researcher 2 5%
Other 8 22%
Unknown 7 19%
Readers by discipline Count As %
Sports and Recreations 10 27%
Biochemistry, Genetics and Molecular Biology 7 19%
Agricultural and Biological Sciences 5 14%
Medicine and Dentistry 4 11%
Physics and Astronomy 1 3%
Other 3 8%
Unknown 7 19%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 2. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 11 October 2023.
All research outputs
#15,739,529
of 25,373,627 outputs
Outputs from Brazilian Journal of Medical and Biological Research
#670
of 1,254 outputs
Outputs of similar age
#177,898
of 290,080 outputs
Outputs of similar age from Brazilian Journal of Medical and Biological Research
#4
of 8 outputs
Altmetric has tracked 25,373,627 research outputs across all sources so far. This one is in the 37th percentile – i.e., 37% of other outputs scored the same or lower than it.
So far Altmetric has tracked 1,254 research outputs from this source. They receive a mean Attention Score of 4.9. This one is in the 46th percentile – i.e., 46% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 290,080 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 37th percentile – i.e., 37% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 8 others from the same source and published within six weeks on either side of this one. This one has scored higher than 4 of them.