Title |
Uso de Intervenções Baseadas em Evidências na Síndrome Coronária Aguda – Subanálise do Registro ACCEPT
|
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Published in |
Arquivos Brasileiros de Cardiologia, February 2014
|
DOI | 10.5935/abc.20140033 |
Pubmed ID | |
Authors |
Ricardo Wang, Fernando Carvalho Neuenschwander, Augusto Lima, Celsa Maria Moreira, Elizabete Silva dos Santos, Helder Jose Lima Reis, Edson Renato Romano, Luiz Alberto Piva e Mattos, Otávio Berwanger, Jadelson Pinheiro de Andrade |
Abstract |
Background: The recommendations in guidelines are based on evidence; however, there is a gap between recommendations and clinical practice. Objective: To describe the practice of prescribing evidence-based treatments for patients with acute coronary syndrome in Brazil. Methods: This study carried out a subanalysis of the ACCEPT registry, assessing epidemiological data and the prescription rate of acetylsalicylic acid, p2y12 inhibitors, antithrombotic drugs, beta-blockers, angiotensin-converting enzyme inhibitors/angiotensin-receptor blockers (IAT1RB), and statins. In addition, the quality of myocardial reperfusion in ST-segment elevation myocardial infarction was evaluated. Results: This study assessed 2,453 patients. The prescription rates of acetylsalicylic acid, p2y12 inhibitors, antithrombotic drugs, beta-blockers, angiotensin-converting enzyme inhibitors/IAT1RB, and statins were as follows: in 24 hours - 97.6%, 89.5%, 89.1%, 80.2%, 67.9% and 90.6%; and at six months - 89.3%, 53.6%, 0%, 74.4%, 57.6% and 85.4%, respectively. Regarding ST-segment elevation myocardial infarction, only 35.9% and 25.3% of the patients underwent primary angioplasty and thrombolysis, respectively, within the recommended times. Conclusion: This registry showed high initial prescription rates of antiplatelet drugs, antithrombotic drugs, and statins, and lower prescription rates of beta-blockers and angiotensin-converting enzyme inhibitors/IAT1RB. Independently of the class, the use of all drugs decreased by six months. Most patients with ST-segment elevation myocardial infarction did not undergo myocardial reperfusion within the time recommended. |
Mendeley readers
Geographical breakdown
Country | Count | As % |
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Unknown | 22 | 100% |
Demographic breakdown
Readers by professional status | Count | As % |
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Student > Postgraduate | 4 | 18% |
Student > Master | 3 | 14% |
Student > Bachelor | 2 | 9% |
Professor > Associate Professor | 1 | 5% |
Researcher | 1 | 5% |
Other | 1 | 5% |
Unknown | 10 | 45% |
Readers by discipline | Count | As % |
---|---|---|
Medicine and Dentistry | 7 | 32% |
Nursing and Health Professions | 2 | 9% |
Pharmacology, Toxicology and Pharmaceutical Science | 1 | 5% |
Immunology and Microbiology | 1 | 5% |
Computer Science | 1 | 5% |
Other | 0 | 0% |
Unknown | 10 | 45% |