PACT promotes the metastasis of basal-like breast cancer through Rac1 SUMOylation and activation

Overview of attention for article published in Oncogene, August 2022

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@RobClarkeLab

RT @oncogenejournal: PACT promotes BLBC metastasis by interacting with SUMO-conjugating enzyme Ubc9 to stimulate the SUMOylation and activa…

PACT promotes BLBC metastasis by interacting with SUMO-conjugating enzyme Ubc9 to stimulate the SUMOylation and activation of Rac1. Could targeting PACT be used with conventional chemotherapy to develop combination therapies to combat #chemoresistance…

In this new @oncogenejournal paper, scientists from the Shanghai University of Traditional Chinese Medicine found that a particular protein activator promotes the metastasis of basal-like #BreastCancer through Rac1 SUMOylation 🤼 and activation. https://…

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