RT @ceciliaNoecker: @SuezLab E. lenta metabolism of digoxin & Th17 activation! https://t.co/ap8SdibaFN and https://t.co/N3NlJCsXNB
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Discovery and characterization of a prevalent human gut bacterial enzyme sufficient for the inactivation of a family of plant toxins. by Koppel N, Bisanz JE, Pandelia ME, Turnbaugh PJ, Balskus EP https://t.co/oADPIN05xM
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In biochemical and toxicological terms, 'they' [our gut microbiome species] are 'us'...here is an interesting dive into the microbial basis of digoxin resistance. I would think this links back to ancestral dietary habits that our microbes co-evolved with.
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RT @pgrnhub: #ASHG18 @PTurnbaugh Cgr2, a cardiac glycoside reductase gene in E. Lenta bacteria is sufficient for digoxin reduction https://…