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Mendeley readers
Attention Score in Context
| Title |
Nanosized hydroxyapatite and other calcium phosphates: Chemistry of formation and application as drug and gene delivery agents
|
|---|---|
| Published in |
Journal of Biomedical Materials Research, Part B: Applied Biomaterials, November 2010
|
| DOI | 10.1002/jbm.b.31746 |
| Pubmed ID | |
| Authors |
Vuk Uskoković, Dragan P. Uskoković |
| Abstract |
The first part of this review looks at the fundamental properties of hydroxyapatite (HAP), the basic mineral constituent of mammalian hard tissues, including the physicochemical features that govern its formation by precipitation. A special emphasis is placed on the analysis of qualities of different methods of synthesis and of the phase transformations intrinsic to the formation of HAP following precipitation from aqueous solutions. This serves as an introduction to the second part and the main subject of this review, which relates to the discourse regarding the prospects of fabrication of ultrafine, nanosized particles based on calcium phosphate carriers with various therapeutic and/or diagnostic agents coated on and/or encapsulated within the particles. It is said that the particles could be either surface-functionalized with amphiphiles, peptides, proteins, or nucleic acids or injected with therapeutic agents, magnetic ions, or fluorescent molecules. Depending on the additive, they could be subsequently used for a variety of applications, including the controlled delivery and release of therapeutic agents (extracellularly or intracellularly), magnetic resonance imaging and hyperthermia therapy, cell separation, blood detoxification, peptide or oligonucleotide chromatography and ultrasensitive detection of biomolecules, and in vivo and in vitro gene transfection. Calcium phosphate nanoparticles as carriers of therapeutic agents that would enable a controlled drug release to treat a given bone infection and at the same be resorbed in the body so as to regenerate hard tissue lost to disease are emphasized hereby as one of the potentially attractive smart materials for the modern medicine. |
Mendeley readers
The data shown below were compiled from readership statistics for 426 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Bangladesh | 1 | <1% |
| France | 1 | <1% |
| Ireland | 1 | <1% |
| Italy | 1 | <1% |
| Latvia | 1 | <1% |
| Sweden | 1 | <1% |
| Canada | 1 | <1% |
| Argentina | 1 | <1% |
| Japan | 1 | <1% |
| Other | 1 | <1% |
| Unknown | 416 | 98% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Student > Ph. D. Student | 82 | 19% |
| Student > Master | 60 | 14% |
| Researcher | 52 | 12% |
| Student > Bachelor | 44 | 10% |
| Student > Doctoral Student | 26 | 6% |
| Other | 55 | 13% |
| Unknown | 107 | 25% |
| Readers by discipline | Count | As % |
|---|---|---|
| Materials Science | 71 | 17% |
| Chemistry | 66 | 15% |
| Engineering | 41 | 10% |
| Agricultural and Biological Sciences | 28 | 7% |
| Medicine and Dentistry | 26 | 6% |
| Other | 67 | 16% |
| Unknown | 127 | 30% |
Attention Score in Context
This research output has an Altmetric Attention Score of 7. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 08 November 2022.
All research outputs
#4,902,784
of 25,643,886 outputs
Outputs from Journal of Biomedical Materials Research, Part B: Applied Biomaterials
#116
of 1,379 outputs
Outputs of similar age
#21,218
of 111,187 outputs
Outputs of similar age from Journal of Biomedical Materials Research, Part B: Applied Biomaterials
#2
of 12 outputs
Altmetric has tracked 25,643,886 research outputs across all sources so far. Compared to these this one has done well and is in the 79th percentile: it's in the top 25% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 1,379 research outputs from this source. They receive a mean Attention Score of 3.9. This one has done particularly well, scoring higher than 90% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 111,187 tracked outputs that were published within six weeks on either side of this one in any source. This one has done well, scoring higher than 79% of its contemporaries.
We're also able to compare this research output to 12 others from the same source and published within six weeks on either side of this one. This one has done well, scoring higher than 83% of its contemporaries.