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X Demographics
Mendeley readers
Attention Score in Context
| Title |
Chilean crab (Aegla cholchol) as a new source of chitin and chitosan with antifungal properties against Candida spp
|
|---|---|
| Published in |
International Journal of Biological Macromolecules, February 2020
|
| DOI | 10.1016/j.ijbiomac.2020.01.126 |
| Pubmed ID | |
| Authors |
Patricia Bernabé, Liliam Becherán, Gustavo Cabrera-Barjas, Aleksandra Nesic, Claudio Alburquenque, Cecilia V. Tapia, Edelio Taboada, Joel Alderete, Patricio De Los Ríos |
| Abstract |
In the present work, the chemical composition of the Chilean freshwater crab Aegla cholchol exoskeleton was studied for the first time. α-Chitin was isolated from three main body parts (pincers, legs, carapace), and its content ranged from 9.0-10.4% (w/w). Moreover, chitosan was extracted by alkaline treatment at different temperature and time regimes. Aegla cholchol exoskeleton, chitin and chitosans were characterized by FTIR, TGA, and SEM. Chemical structure of chitin and chitosan was confirmed by NMR spectroscopy. Chitosan molecular weight determinations were carried out by GPC. The obtained chitosan samples had a degree of N-acetylation (DA) between 4 and 15% and molecular weight (Mw) in the range of 65-201 kDa. The antifungal activity of the chitosan samples and the chitooligomer were tested toward twenty isolated clinical strains of Candida yeast. Chitosan with lower DA (4%) and higher molecular weight showed the lowest minimum inhibitory concentration (MIC) values, which was evidenced by the highest antifungal activity toward Candida albicans, Candida tropicalis, Candida glabrata, and Candida parapsilosis. Results suggest that Aegla cholchol is an excellent natural source for production of bioactive materials with potential applications in the health system, to prevent infections associated with Candida strains. |
X Demographics
The data shown below were collected from the profiles of 2 X users who shared this research output. Click here to find out more about how the information was compiled.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| United States | 1 | 50% |
| Unknown | 1 | 50% |
Demographic breakdown
| Type | Count | As % |
|---|---|---|
| Members of the public | 2 | 100% |
Mendeley readers
The data shown below were compiled from readership statistics for 95 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Unknown | 95 | 100% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Researcher | 11 | 12% |
| Student > Bachelor | 11 | 12% |
| Student > Master | 10 | 11% |
| Student > Ph. D. Student | 8 | 8% |
| Unspecified | 5 | 5% |
| Other | 16 | 17% |
| Unknown | 34 | 36% |
| Readers by discipline | Count | As % |
|---|---|---|
| Agricultural and Biological Sciences | 10 | 11% |
| Biochemistry, Genetics and Molecular Biology | 9 | 9% |
| Chemical Engineering | 9 | 9% |
| Engineering | 6 | 6% |
| Chemistry | 6 | 6% |
| Other | 19 | 20% |
| Unknown | 36 | 38% |
Attention Score in Context
This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 02 February 2020.
All research outputs
#19,957,118
of 25,387,668 outputs
Outputs from International Journal of Biological Macromolecules
#4,171
of 7,507 outputs
Outputs of similar age
#336,539
of 471,099 outputs
Outputs of similar age from International Journal of Biological Macromolecules
#128
of 254 outputs
Altmetric has tracked 25,387,668 research outputs across all sources so far. This one is in the 18th percentile – i.e., 18% of other outputs scored the same or lower than it.
So far Altmetric has tracked 7,507 research outputs from this source. They receive a mean Attention Score of 2.9. This one is in the 40th percentile – i.e., 40% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 471,099 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 24th percentile – i.e., 24% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 254 others from the same source and published within six weeks on either side of this one. This one is in the 45th percentile – i.e., 45% of its contemporaries scored the same or lower than it.