Title |
Homocysteine: cardiovascular risk factor in children and adolescents?
|
---|---|
Published in |
Revista da Associação Médica Brasileira, October 2013
|
DOI | 10.1016/j.ramb.2013.05.004 |
Pubmed ID | |
Authors |
Adriana Amorim De Farias Leal, Ástrid Camêlo Palmeira, Gabriella Menezes Almeida De Castro, Mônica Oliveira Da Silva Simões, Alessandra Teixeira Ramos, Carla Campos Muniz Medeiros |
Abstract |
The aim of this study was to identify publications in literature that investigated Homocysteine (He) as a risk factor for CVD among children and adolescents. An active search for information in LILACS, IBECS, Science Direct, Medline and Cochrane Library databases was conducted using the following combination of keywords "homocysteine", "cardiovascular diseases", "child" and "adolescent". Fifteen articles were analyzed showing direct relationship with increasing age (8 studies) and male gender (10 studies), and an inverse relationship with serum vitamins B6, B12 and folate levels. Thus, the results suggest that more research must be carried through in order to determine in a more coherent way the causes of the hiperhomocisteinemia in the pediatric population, guiding for an adequate diet, rich in nutrients necessary to favor the metabolism of the He. |
Mendeley readers
Geographical breakdown
Country | Count | As % |
---|---|---|
Romania | 1 | 2% |
Brazil | 1 | 2% |
Unknown | 40 | 95% |
Demographic breakdown
Readers by professional status | Count | As % |
---|---|---|
Student > Postgraduate | 7 | 17% |
Student > Master | 7 | 17% |
Student > Bachelor | 6 | 14% |
Student > Doctoral Student | 4 | 10% |
Researcher | 3 | 7% |
Other | 8 | 19% |
Unknown | 7 | 17% |
Readers by discipline | Count | As % |
---|---|---|
Medicine and Dentistry | 13 | 31% |
Nursing and Health Professions | 5 | 12% |
Agricultural and Biological Sciences | 5 | 12% |
Pharmacology, Toxicology and Pharmaceutical Science | 2 | 5% |
Social Sciences | 2 | 5% |
Other | 7 | 17% |
Unknown | 8 | 19% |