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| Title |
Immune System Dysfunction in the Elderly
|
|---|---|
| Published in |
Anais da Academia Brasileira de Ciências, January 2017
|
| DOI | 10.1590/0001-3765201720160487 |
| Pubmed ID | |
| Authors | |
| Abstract |
Human aging is characterized by both physical and physiological frailty that profoundly affects the immune system. In this context aging is associated with declines in adaptive and innate immunity established as immunosenescence. Immunosenescence is a new concept that reflects the age-associated restructuring changes of innate and adaptive immune functions. Thus elderly individuals usually present chronic low-level inflammation, higher infection rates and chronic diseases. A study of alterations in the immune system during aging could provide a potentially useful biomarker for the evaluation of immune senescence treatment. The immune system is the result of the interplay between innate and adaptive immunity, yet the impact of aging on this function is unclear. In this article the function of the immune system during aging is explored. |
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X Demographics
The data shown below were collected from the profile of 1 X user who shared this research output. Click here to find out more about how the information was compiled.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| United Kingdom | 1 | 100% |
Demographic breakdown
| Type | Count | As % |
|---|---|---|
| Members of the public | 1 | 100% |
Mendeley demographics
The data shown below were compiled from readership statistics for 457 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Unknown | 457 | 100% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Student > Bachelor | 74 | 16% |
| Student > Master | 51 | 11% |
| Student > Ph. D. Student | 27 | 6% |
| Researcher | 24 | 5% |
| Student > Postgraduate | 23 | 5% |
| Other | 64 | 14% |
| Unknown | 194 | 42% |
| Readers by discipline | Count | As % |
|---|---|---|
| Medicine and Dentistry | 103 | 23% |
| Biochemistry, Genetics and Molecular Biology | 34 | 7% |
| Immunology and Microbiology | 30 | 7% |
| Nursing and Health Professions | 21 | 5% |
| Agricultural and Biological Sciences | 10 | 2% |
| Other | 45 | 10% |
| Unknown | 214 | 47% |