Title |
Relationship of systemic, hepatosplanchnic, and microcirculatory perfusion parameters with 6-hour lactate clearance in hyperdynamic septic shock patients: an acute, clinical-physiological, pilot study
|
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Published in |
Annals of Intensive Care, October 2012
|
DOI | 10.1186/2110-5820-2-44 |
Pubmed ID | |
Authors |
Glenn Hernandez, Tomas Regueira, Alejandro Bruhn, Ricardo Castro, Maximiliano Rovegno, Andrea Fuentealba, Enrique Veas, Dolores Berrutti, Jorge Florez, Eduardo Kattan, Celeste Martin, Can Ince |
Abstract |
Recent clinical studies have confirmed the strong prognostic value of persistent hyperlactatemia and delayed lactate clearance in septic shock. Several potential hypoxic and nonhypoxic mechanisms have been associated with persistent hyperlactatemia, but the relative contribution of these factors has not been specifically addressed in comprehensive clinical physiological studies. Our goal was to determine potential hemodynamic and perfusion-related parameters associated with 6-hour lactate clearance in a cohort of hyperdynamic, hyperlactatemic, septic shock patients. |
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Mendeley readers
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