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Increasing Blood Glucose Variability Is a Precursor of Sepsis and Mortality in Burned Patients

Overview of attention for article published in PLOS ONE, October 2012
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  • Above-average Attention Score compared to outputs of the same age and source (51st percentile)

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3 X users

Citations

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38 Dimensions

Readers on

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49 Mendeley
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Title
Increasing Blood Glucose Variability Is a Precursor of Sepsis and Mortality in Burned Patients
Published in
PLOS ONE, October 2012
DOI 10.1371/journal.pone.0046582
Pubmed ID
Authors

Alexander N. Pisarchik, Olga N. Pochepen, Liudmila A. Pisarchyk

Abstract

High glycemic variability, rather than a mean glucose level, is an important factor associated with sepsis and hospital mortality in critically ill patients. In this retrospective study we analyze the blood glucose data of 172 nondiabetic patients 18-60 yrs old with second and third-degree burns of total body surface area greater than 30% and 5%, respectively, admitted to ICU in 2004-2008. The analysis identified significant association of increasing daily glucose excursion (DELTA) accompanied by evident episodes of hyperglycemia (>11 mmol/l) and hypoglycemia (<2.8 mmol/l), with sepsis and forthcoming death, even when the mean daily glucose was within a range of acceptable glycemia. No association was found in sepsis complication and hospital mortality with doses of intravenous insulin and glucose infusion. A strong increase in DELTA before sepsis and death is treated as fluctuation amplification near the onset of dynamical instability.

X Demographics

X Demographics

The data shown below were collected from the profiles of 3 X users who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 49 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
United Kingdom 1 2%
Unknown 48 98%

Demographic breakdown

Readers by professional status Count As %
Student > Master 8 16%
Researcher 8 16%
Student > Postgraduate 5 10%
Student > Doctoral Student 4 8%
Student > Ph. D. Student 4 8%
Other 8 16%
Unknown 12 24%
Readers by discipline Count As %
Medicine and Dentistry 24 49%
Physics and Astronomy 3 6%
Nursing and Health Professions 2 4%
Immunology and Microbiology 2 4%
Agricultural and Biological Sciences 2 4%
Other 2 4%
Unknown 14 29%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 3. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 18 October 2012.
All research outputs
#13,271,134
of 22,681,577 outputs
Outputs from PLOS ONE
#105,747
of 193,576 outputs
Outputs of similar age
#92,490
of 172,685 outputs
Outputs of similar age from PLOS ONE
#2,224
of 4,570 outputs
Altmetric has tracked 22,681,577 research outputs across all sources so far. This one is in the 41st percentile – i.e., 41% of other outputs scored the same or lower than it.
So far Altmetric has tracked 193,576 research outputs from this source. They typically receive a lot more attention than average, with a mean Attention Score of 15.0. This one is in the 45th percentile – i.e., 45% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 172,685 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 46th percentile – i.e., 46% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 4,570 others from the same source and published within six weeks on either side of this one. This one has gotten more attention than average, scoring higher than 51% of its contemporaries.