Vitamin K Vitamers Differently Affect Energy Metabolism in IPEC-J2 Cells

RT @renesugar: Vitamin K Vitamers Differently Affect Energy Metabolism in IPEC-J2 Cells https://t.co/ENEuSneSYE

https://t.co/ENEuSnx2cM "VK2 can mimic the two structural components of CoQ10 which are crucial in OXPHOS, namely in the naphthoquinone core, which transfer electrons during the redox-cycle, and in the isoprenoid tail, which allows diffusion into the lipi

https://t.co/ENEuSnx2cM "The VK2 at 5 μM only stimulates ATP production by OXPHOS." "Conversely, 10 μM VK3, which lacks the long side chain, inhibits OXPHOS by 30% and glycolysis by 45%."

https://t.co/ENEuSneSYE "The VK1, which has a long hydrocarbon chain, at both concentrations (5 and 10 μM), increases the cellular ATP production due to oxidative phosphorylation (OXPHOS) by 5% and by 30% through glycolysis."