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Hypoxia and its implications in rheumatoid arthritis

Overview of attention for article published in Journal of Biomedical Science, August 2016
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Title
Hypoxia and its implications in rheumatoid arthritis
Published in
Journal of Biomedical Science, August 2016
DOI 10.1186/s12929-016-0281-0
Pubmed ID
Authors

Celia María Quiñonez-Flores, Susana Aideé González-Chávez, César Pacheco-Tena

Abstract

Alterations in tissue oxygen pressure contribute to a number of diseases, including rheumatoid arthritis (RA). Low partial pressure of oxygen, a condition known as hypoxia, is a relevant feature in RA since it is involved in angiogenesis, inflammation, apoptosis, cartilage degradation, energy metabolism, and oxidative damage. Therefore, alterations in hypoxia-related signaling pathways are considered potential mechanisms of disease pathogenesis. The objective of this review is to highlight and update our current knowledge of the role of hypoxia in the pathogenesis of RA. We describe the experimental evidence that RA synovial tissue exists in a hypoxic state, as well as the origin and involvement of synovial hypoxia in different aspects of the pathogenic process.

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The data shown below were collected from the profile of 1 X user who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 96 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Bulgaria 1 1%
Unknown 95 99%

Demographic breakdown

Readers by professional status Count As %
Student > Ph. D. Student 21 22%
Student > Master 11 11%
Researcher 10 10%
Student > Bachelor 10 10%
Student > Doctoral Student 8 8%
Other 9 9%
Unknown 27 28%
Readers by discipline Count As %
Biochemistry, Genetics and Molecular Biology 15 16%
Immunology and Microbiology 12 13%
Medicine and Dentistry 12 13%
Agricultural and Biological Sciences 11 11%
Pharmacology, Toxicology and Pharmaceutical Science 5 5%
Other 14 15%
Unknown 27 28%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 24 August 2016.
All research outputs
#22,758,309
of 25,371,288 outputs
Outputs from Journal of Biomedical Science
#969
of 1,100 outputs
Outputs of similar age
#314,873
of 355,231 outputs
Outputs of similar age from Journal of Biomedical Science
#11
of 13 outputs
Altmetric has tracked 25,371,288 research outputs across all sources so far. This one is in the 1st percentile – i.e., 1% of other outputs scored the same or lower than it.
So far Altmetric has tracked 1,100 research outputs from this source. They typically receive a lot more attention than average, with a mean Attention Score of 11.0. This one is in the 1st percentile – i.e., 1% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 355,231 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 1st percentile – i.e., 1% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 13 others from the same source and published within six weeks on either side of this one. This one is in the 1st percentile – i.e., 1% of its contemporaries scored the same or lower than it.