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Identification of Genetic Suppressors of the Sin3A Knockdown Wing Phenotype

Overview of attention for article published in PLOS ONE, November 2012
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Title
Identification of Genetic Suppressors of the Sin3A Knockdown Wing Phenotype
Published in
PLOS ONE, November 2012
DOI 10.1371/journal.pone.0049563
Pubmed ID
Authors

Aishwarya Swaminathan, Valerie L. Barnes, Stephanie Fox, Sarah Gammouh, Lori A. Pile

Abstract

The role of the Sin3A transcriptional corepressor in regulating the cell cycle is established in various metazoans. Little is known, however, about the signaling pathways that trigger or are triggered by Sin3A function. To discover genes that work in similar or opposing pathways to Sin3A during development, we have performed an unbiased screen of deficiencies of the Drosophila third chromosome. Additionally, we have performed a targeted loss of function screen to identify cell cycle genes that genetically interact with Sin3A. We have identified genes that encode proteins involved in regulation of gene expression, signaling pathways and cell cycle that can suppress the curved wing phenotype caused by the knockdown of Sin3A. These data indicate that Sin3A function is quite diverse and impacts a wide variety of cellular processes.

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The data shown below were collected from the profile of 1 X user who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 13 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Brazil 1 8%
Unknown 12 92%

Demographic breakdown

Readers by professional status Count As %
Student > Ph. D. Student 4 31%
Researcher 3 23%
Student > Bachelor 1 8%
Unspecified 1 8%
Student > Master 1 8%
Other 1 8%
Unknown 2 15%
Readers by discipline Count As %
Agricultural and Biological Sciences 8 62%
Unspecified 1 8%
Biochemistry, Genetics and Molecular Biology 1 8%
Environmental Science 1 8%
Unknown 2 15%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 22 November 2012.
All research outputs
#18,321,703
of 22,687,320 outputs
Outputs from PLOS ONE
#153,900
of 193,653 outputs
Outputs of similar age
#136,106
of 178,791 outputs
Outputs of similar age from PLOS ONE
#3,463
of 4,728 outputs
Altmetric has tracked 22,687,320 research outputs across all sources so far. This one is in the 11th percentile – i.e., 11% of other outputs scored the same or lower than it.
So far Altmetric has tracked 193,653 research outputs from this source. They typically receive a lot more attention than average, with a mean Attention Score of 15.0. This one is in the 10th percentile – i.e., 10% of its peers scored the same or lower than it.
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