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Animal Models of Nonalcoholic Steatohepatitis: Eat, Delete, and Inflame

Overview of attention for article published in Digestive Diseases and Sciences, December 2015
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About this Attention Score

  • In the top 25% of all research outputs scored by Altmetric
  • Good Attention Score compared to outputs of the same age (79th percentile)
  • High Attention Score compared to outputs of the same age and source (83rd percentile)

Mentioned by

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1 X user
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4 patents

Readers on

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228 Mendeley
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Title
Animal Models of Nonalcoholic Steatohepatitis: Eat, Delete, and Inflame
Published in
Digestive Diseases and Sciences, December 2015
DOI 10.1007/s10620-015-3977-1
Pubmed ID
Authors

Samar H. Ibrahim, Petra Hirsova, Harmeet Malhi, Gregory J. Gores

Abstract

With the obesity epidemic, nonalcoholic fatty liver disease (NAFLD) has become a public health problem with increasing prevalence. The mechanism of disease progression remains obscure and effective therapy is lacking. Therefore, there is a need to understand the pathogenic mechanisms responsible for disease development and progression in order to develop innovative therapies. To accomplish this goal, experimental animal models that recapitulate the human disease are necessary, especially, since causative mechanistic studies of NAFLD are more difficult or unethical to perform in humans. A large number of studies regarding the pathophysiology and treatment of nonalcoholic steatohepatitis (NASH) have been undertaken in mice to model human NAFLD and NASH. This review discusses the known dietary, genetic, and inflammation-based animal models of NASH described in recent years, with a focus on the major advances made in this field.

X Demographics

X Demographics

The data shown below were collected from the profile of 1 X user who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 228 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
United States 1 <1%
Belgium 1 <1%
Unknown 226 99%

Demographic breakdown

Readers by professional status Count As %
Student > Ph. D. Student 42 18%
Researcher 38 17%
Student > Master 23 10%
Student > Bachelor 22 10%
Other 8 4%
Other 27 12%
Unknown 68 30%
Readers by discipline Count As %
Biochemistry, Genetics and Molecular Biology 51 22%
Medicine and Dentistry 29 13%
Agricultural and Biological Sciences 25 11%
Pharmacology, Toxicology and Pharmaceutical Science 21 9%
Engineering 5 2%
Other 24 11%
Unknown 73 32%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 7. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 21 May 2022.
All research outputs
#4,823,223
of 23,854,458 outputs
Outputs from Digestive Diseases and Sciences
#698
of 4,304 outputs
Outputs of similar age
#78,562
of 394,024 outputs
Outputs of similar age from Digestive Diseases and Sciences
#9
of 55 outputs
Altmetric has tracked 23,854,458 research outputs across all sources so far. Compared to these this one has done well and is in the 79th percentile: it's in the top 25% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 4,304 research outputs from this source. They typically receive a little more attention than average, with a mean Attention Score of 5.8. This one has done well, scoring higher than 83% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 394,024 tracked outputs that were published within six weeks on either side of this one in any source. This one has done well, scoring higher than 79% of its contemporaries.
We're also able to compare this research output to 55 others from the same source and published within six weeks on either side of this one. This one has done well, scoring higher than 83% of its contemporaries.