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Surveillance of hemorrhagic fever and/or neuroinvasive disease: challenges of diagnosis

Overview of attention for article published in Revista de Saúde Pública, June 2021
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Title
Surveillance of hemorrhagic fever and/or neuroinvasive disease: challenges of diagnosis
Published in
Revista de Saúde Pública, June 2021
DOI 10.11606/s1518-8787.2021055003068
Pubmed ID
Authors

Leonardo José Tadeu de Araújo, Lorenzo Lang Gonzalez, Lewis Fletcher Buss, Juliana Mariotti Guerra, David Salas Gomez, Camila Santos da Silva Ferreira, Cinthya Santos Cirqueira, Fábio Ghillardi, Steven S. Witkin, Ester Cerdeira Sabino

Abstract

To evaluate the performance of post mortem laboratory analysis in identifying the causes of hemorrhagic fever and/or neuroinvasive disease in deaths by arbovirus infection. Retrospective cross-sectional study based on the differential analysis and final outcome obtained in patients whose samples underwent laboratory testing for arboviruses at the Pathology Center of the Adolfo Lutz Institute, in São Paulo, Brazil. Of the 1355 adults clinically diagnosed with hemorrhagic fever and/or neuroinvasive disease, the most commonly attributed cause of death and the most common final outcome was dengue fever. Almost half of the samples tested negative on all laboratory tests conducted. The failure to identify the causative agent in a great number of cases highlights a gap in the diagnosis of deaths of unknown etiology. Additional immunohistochemical and molecular assessments need to be added to the post-mortem protocol if all laboratory evaluations performed fail to identify a causative agent. While part of our findings may be due to technical issues related to sample fixation, better information availability when making the initial diagnosis is crucial. Including molecular approaches might lead to a significant advancement in diagnostic accuracy.

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The data shown below were collected from the profiles of 3 X users who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 25 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Unknown 25 100%

Demographic breakdown

Readers by professional status Count As %
Student > Master 4 16%
Lecturer 2 8%
Student > Postgraduate 2 8%
Librarian 1 4%
Student > Doctoral Student 1 4%
Other 3 12%
Unknown 12 48%
Readers by discipline Count As %
Medicine and Dentistry 5 20%
Unspecified 1 4%
Agricultural and Biological Sciences 1 4%
Biochemistry, Genetics and Molecular Biology 1 4%
Social Sciences 1 4%
Other 1 4%
Unknown 15 60%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 01 July 2021.
All research outputs
#17,297,846
of 25,392,582 outputs
Outputs from Revista de Saúde Pública
#690
of 1,139 outputs
Outputs of similar age
#277,525
of 454,785 outputs
Outputs of similar age from Revista de Saúde Pública
#17
of 17 outputs
Altmetric has tracked 25,392,582 research outputs across all sources so far. This one is in the 21st percentile – i.e., 21% of other outputs scored the same or lower than it.
So far Altmetric has tracked 1,139 research outputs from this source. They receive a mean Attention Score of 4.7. This one is in the 23rd percentile – i.e., 23% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 454,785 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 28th percentile – i.e., 28% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 17 others from the same source and published within six weeks on either side of this one. This one is in the 1st percentile – i.e., 1% of its contemporaries scored the same or lower than it.