Title |
OpenMS: a flexible open-source software platform for mass spectrometry data analysis
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Published in |
Nature Methods, August 2016
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DOI | 10.1038/nmeth.3959 |
Pubmed ID | |
Authors |
Hannes L Röst, Timo Sachsenberg, Stephan Aiche, Chris Bielow, Hendrik Weisser, Fabian Aicheler, Sandro Andreotti, Hans-Christian Ehrlich, Petra Gutenbrunner, Erhan Kenar, Xiao Liang, Sven Nahnsen, Lars Nilse, Julianus Pfeuffer, George Rosenberger, Marc Rurik, Uwe Schmitt, Johannes Veit, Mathias Walzer, David Wojnar, Witold E Wolski, Oliver Schilling, Jyoti S Choudhary, Lars Malmström, Ruedi Aebersold, Knut Reinert, Oliver Kohlbacher |
Abstract |
High-resolution mass spectrometry (MS) has become an important tool in the life sciences, contributing to the diagnosis and understanding of human diseases, elucidating biomolecular structural information and characterizing cellular signaling networks. However, the rapid growth in the volume and complexity of MS data makes transparent, accurate and reproducible analysis difficult. We present OpenMS 2.0 (http://www.openms.de), a robust, open-source, cross-platform software specifically designed for the flexible and reproducible analysis of high-throughput MS data. The extensible OpenMS software implements common mass spectrometric data processing tasks through a well-defined application programming interface in C++ and Python and through standardized open data formats. OpenMS additionally provides a set of 185 tools and ready-made workflows for common mass spectrometric data processing tasks, which enable users to perform complex quantitative mass spectrometric analyses with ease. |
X Demographics
Geographical breakdown
Country | Count | As % |
---|---|---|
United States | 6 | 16% |
Germany | 6 | 16% |
United Kingdom | 5 | 13% |
France | 2 | 5% |
Egypt | 1 | 3% |
South Africa | 1 | 3% |
Canada | 1 | 3% |
Switzerland | 1 | 3% |
Belgium | 1 | 3% |
Other | 1 | 3% |
Unknown | 13 | 34% |
Demographic breakdown
Type | Count | As % |
---|---|---|
Members of the public | 20 | 53% |
Scientists | 17 | 45% |
Science communicators (journalists, bloggers, editors) | 1 | 3% |
Mendeley readers
Geographical breakdown
Country | Count | As % |
---|---|---|
United States | 5 | <1% |
United Kingdom | 4 | <1% |
Germany | 3 | <1% |
Switzerland | 1 | <1% |
France | 1 | <1% |
Brazil | 1 | <1% |
Japan | 1 | <1% |
China | 1 | <1% |
Unknown | 682 | 98% |
Demographic breakdown
Readers by professional status | Count | As % |
---|---|---|
Student > Ph. D. Student | 157 | 22% |
Researcher | 132 | 19% |
Student > Master | 77 | 11% |
Student > Bachelor | 72 | 10% |
Other | 32 | 5% |
Other | 90 | 13% |
Unknown | 139 | 20% |
Readers by discipline | Count | As % |
---|---|---|
Biochemistry, Genetics and Molecular Biology | 158 | 23% |
Agricultural and Biological Sciences | 120 | 17% |
Chemistry | 99 | 14% |
Computer Science | 38 | 5% |
Pharmacology, Toxicology and Pharmaceutical Science | 29 | 4% |
Other | 88 | 13% |
Unknown | 167 | 24% |