Title |
ATRP in the design of functional materials for biomedical applications
|
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Published in |
Progress in Polymer Science, August 2011
|
DOI | 10.1016/j.progpolymsci.2011.08.001 |
Pubmed ID | |
Authors |
Daniel J. Siegwart, Jung Kwon Oh, Krzysztof Matyjaszewski |
Abstract |
Atom Transfer Radical Polymerization (ATRP) is an effective technique for the design and preparation of multifunctional, nanostructured materials for a variety of applications in biology and medicine. ATRP enables precise control over macromolecular structure, order, and functionality, which are important considerations for emerging biomedical designs. This article reviews recent advances in the preparation of polymer-based nanomaterials using ATRP, including polymer bioconjugates, block copolymer-based drug delivery systems, cross-linked microgels/nanogels, diagnostic and imaging platforms, tissue engineering hydrogels, and degradable polymers. It is envisioned that precise engineering at the molecular level will translate to tailored macroscopic physical properties, thus enabling control of the key elements for realized biomedical applications. |
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Geographical breakdown
Country | Count | As % |
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India | 3 | <1% |
Germany | 2 | <1% |
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Canada | 2 | <1% |
Spain | 2 | <1% |
Mexico | 2 | <1% |
Czechia | 1 | <1% |
Hong Kong | 1 | <1% |
Other | 7 | 1% |
Unknown | 514 | 95% |
Demographic breakdown
Readers by professional status | Count | As % |
---|---|---|
Student > Ph. D. Student | 146 | 27% |
Student > Master | 77 | 14% |
Researcher | 59 | 11% |
Student > Doctoral Student | 50 | 9% |
Student > Bachelor | 43 | 8% |
Other | 68 | 13% |
Unknown | 96 | 18% |
Readers by discipline | Count | As % |
---|---|---|
Chemistry | 220 | 41% |
Materials Science | 61 | 11% |
Engineering | 40 | 7% |
Chemical Engineering | 28 | 5% |
Agricultural and Biological Sciences | 24 | 4% |
Other | 52 | 10% |
Unknown | 114 | 21% |