RANTES/CCL5 Induces Collagen Degradation by Activating MMP-1 and MMP-13 Expression in Human Rheumatoid Arthritis Synovial Fibroblasts

@BinitaKane Perhaps connective tissue damage is immune mediated? Eg CCL5 (RANTES) is elevated in many long haulers and pwME and has been shown to have an effect on tissue degrading enzymes MMP-1 and MMP-13 expression https://t.co/PCDhU7gd9u.

@YoDoctorYo @brucep13 @JosephKulandai @ME_CFS @JanetDafoe @DafoeWhitney Could role of CCL5 in collagen degradation explain why many people with ME have hypermobility? https://t.co/PCDhU7gd9u