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Using Plasma Viral Load to Guide Antiretroviral Therapy Initiation to Prevent HIV-1 Transmission

Overview of attention for article published in PLOS ONE, November 2012
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Title
Using Plasma Viral Load to Guide Antiretroviral Therapy Initiation to Prevent HIV-1 Transmission
Published in
PLOS ONE, November 2012
DOI 10.1371/journal.pone.0051192
Pubmed ID
Authors

Pamela M. Murnane, James P. Hughes, Connie Celum, Jairam R. Lingappa, Nelly Mugo, Carey Farquhar, James Kiarie, Anna Wald, Jared M. Baeten, Connie Celum, Anna Wald, Jairam Lingappa, Jared M. Baeten, Mary Campbell, Lawrence Corey, Robert W. Coombs, James P. Hughes, Amalia Magaret, M. Juliana McElrath, Rhoda Morrow, James I. Mullins, David Coetzee, Kenneth Fife, Edwin Were, Max Essex, Joseph Makhema, Elly Katabira, Allan Ronald, Susan Allen, Kayitesi Kayitenkore, Etienne Karita, Elizabeth Bukusi, Craig Cohen, Susan Allen, William Kanweka, Susan Allen, Bellington Vwalika, Saidi Kapiga, Rachel Manongi, Carey Farquhar, Grace John-Stewart, James Kiarie, Susan Allen, Mubiana Inambao, Sinead Delany-Moretlwe, Helen Rees, Guy de Bruyn, Glenda Gray, James McIntyre, Nelly Rwamba Mugo

Abstract

Current WHO guidelines recommend antiretroviral therapy (ART) initiation at CD4 counts ≤350 cells/µL. Increasing this threshold has been proposed, with a primary goal of reducing HIV-1 infectiousness. Because the quantity of HIV-1 in plasma is the primary predictor of HIV-1 transmission, consideration of plasma viral load in ART initiation guidelines is warranted.

X Demographics

X Demographics

The data shown below were collected from the profiles of 3 X users who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 60 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
United Kingdom 1 2%
Japan 1 2%
Portugal 1 2%
Italy 1 2%
Unknown 56 93%

Demographic breakdown

Readers by professional status Count As %
Student > Ph. D. Student 9 15%
Researcher 7 12%
Professor 6 10%
Student > Master 6 10%
Student > Bachelor 5 8%
Other 17 28%
Unknown 10 17%
Readers by discipline Count As %
Medicine and Dentistry 22 37%
Agricultural and Biological Sciences 5 8%
Social Sciences 5 8%
Nursing and Health Professions 4 7%
Psychology 3 5%
Other 12 20%
Unknown 9 15%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 2. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 29 April 2020.
All research outputs
#13,876,749
of 22,687,320 outputs
Outputs from PLOS ONE
#111,831
of 193,653 outputs
Outputs of similar age
#162,109
of 276,634 outputs
Outputs of similar age from PLOS ONE
#2,415
of 4,722 outputs
Altmetric has tracked 22,687,320 research outputs across all sources so far. This one is in the 37th percentile – i.e., 37% of other outputs scored the same or lower than it.
So far Altmetric has tracked 193,653 research outputs from this source. They typically receive a lot more attention than average, with a mean Attention Score of 15.0. This one is in the 40th percentile – i.e., 40% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 276,634 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 40th percentile – i.e., 40% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 4,722 others from the same source and published within six weeks on either side of this one. This one is in the 47th percentile – i.e., 47% of its contemporaries scored the same or lower than it.