Title |
The emergence of HIV-1 primary drug resistance genotypes among treatment-naïve men who have sex with men in high-prevalence areas in China
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Published in |
Archives of Virology, December 2012
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DOI | 10.1007/s00705-012-1557-7 |
Pubmed ID | |
Authors |
Juan Yang, Hui Xing, Jianli Niu, Lingjie Liao, Yuhua Ruan, Xiang He, Yi Feng, Zhe Li, Yiming Shao |
Abstract |
The prevalence of HIV-1 infection in men who have sex with men (MSM) in China has drastically increased, and circulating strains may have acquired transmitted drug resistance (TDR). We determined TDR genotypes among antiretroviral therapy (ART)-naïve MSM in 19 provinces/cities where HIV-1 prevalence among MSM is high, and found an overall 4.9 % TDR rate. Although protease inhibitors (PI) were not in the first-line antiretroviral drug list provided through the National ART Program, 70.4 % of the detected TDR belongs to this category. Our findings confirm the urgent need for TDR surveillance in order to optimize treatment effects of the National ART Program. |
X Demographics
Geographical breakdown
Country | Count | As % |
---|---|---|
United States | 1 | 50% |
Unknown | 1 | 50% |
Demographic breakdown
Type | Count | As % |
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Members of the public | 2 | 100% |
Mendeley readers
Geographical breakdown
Country | Count | As % |
---|---|---|
Hong Kong | 1 | 4% |
Unknown | 23 | 96% |
Demographic breakdown
Readers by professional status | Count | As % |
---|---|---|
Researcher | 5 | 21% |
Other | 3 | 13% |
Student > Ph. D. Student | 3 | 13% |
Professor | 2 | 8% |
Student > Master | 2 | 8% |
Other | 2 | 8% |
Unknown | 7 | 29% |
Readers by discipline | Count | As % |
---|---|---|
Medicine and Dentistry | 10 | 42% |
Immunology and Microbiology | 2 | 8% |
Environmental Science | 1 | 4% |
Mathematics | 1 | 4% |
Nursing and Health Professions | 1 | 4% |
Other | 2 | 8% |
Unknown | 7 | 29% |