Title |
The expression of HSP27 is associated with poor clinical outcome in intrahepatic cholangiocarcinoma
|
---|---|
Published in |
BMC Cancer, December 2007
|
DOI | 10.1186/1471-2407-7-232 |
Pubmed ID | |
Authors |
Antonello A Romani, Pellegrino Crafa, Silvia Desenzani, Gallia Graiani, Costanza Lagrasta, Mario Sianesi, Paolo Soliani, Angelo F Borghetti |
Abstract |
The heat shock proteins (HSPs) 27-kDa (HSP27) and 72-kDa (HSP72), are ubiquitous chaperone molecules inducible in cells exposed to different stress conditions. Increased level of HSPs are reported in several human cancers, and found to be associated with the resistance to some anticancer treatments and poor prognosis. However, there is no study of the relationship between HSPs expression and patient's prognosis in intrahepatic cholangiocarcinoma (IHCCA). In this exploratory retrospective study, we investigated the expressions of HSP27 and HSP72 as potential prognostic factors in IHCCA. |
X Demographics
Geographical breakdown
Country | Count | As % |
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Central African Republic | 1 | 100% |
Demographic breakdown
Type | Count | As % |
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Members of the public | 1 | 100% |
Mendeley readers
Geographical breakdown
Country | Count | As % |
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Unknown | 28 | 100% |
Demographic breakdown
Readers by professional status | Count | As % |
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Researcher | 9 | 32% |
Student > Ph. D. Student | 6 | 21% |
Student > Bachelor | 2 | 7% |
Student > Master | 2 | 7% |
Professor > Associate Professor | 2 | 7% |
Other | 2 | 7% |
Unknown | 5 | 18% |
Readers by discipline | Count | As % |
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Medicine and Dentistry | 7 | 25% |
Agricultural and Biological Sciences | 7 | 25% |
Biochemistry, Genetics and Molecular Biology | 4 | 14% |
Psychology | 2 | 7% |
Unspecified | 1 | 4% |
Other | 2 | 7% |
Unknown | 5 | 18% |