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Oncolytic vaccinia virus GLV-1h68 strain shows enhanced replication in human breast cancer stem-like cells in comparison to breast cancer cells

Overview of attention for article published in Journal of Translational Medicine, August 2012
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About this Attention Score

  • In the top 25% of all research outputs scored by Altmetric
  • High Attention Score compared to outputs of the same age (80th percentile)
  • Good Attention Score compared to outputs of the same age and source (75th percentile)

Mentioned by

patent
13 patents
facebook
1 Facebook page

Citations

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48 Dimensions

Readers on

mendeley
45 Mendeley
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Title
Oncolytic vaccinia virus GLV-1h68 strain shows enhanced replication in human breast cancer stem-like cells in comparison to breast cancer cells
Published in
Journal of Translational Medicine, August 2012
DOI 10.1186/1479-5876-10-167
Pubmed ID
Authors

Huiqiang Wang, Nanhai G Chen, Boris R Minev, Aladar A Szalay

Abstract

Recent data suggest that cancer stem cells (CSCs) play an important role in cancer, as these cells possess enhanced tumor-forming capabilities and are responsible for relapses after apparently curative therapies have been undertaken. Hence, novel cancer therapies will be needed to test for both tumor regression and CSC targeting. The use of oncolytic vaccinia virus (VACV) represents an attractive anti-tumor approach and is currently under evaluation in clinical trials. The purpose of this study was to demonstrate whether VACV does kill CSCs that are resistant to irradiation and chemotherapy.

Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 45 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
United States 1 2%
Germany 1 2%
Italy 1 2%
Unknown 42 93%

Demographic breakdown

Readers by professional status Count As %
Student > Ph. D. Student 9 20%
Researcher 9 20%
Student > Bachelor 8 18%
Student > Master 5 11%
Student > Doctoral Student 3 7%
Other 6 13%
Unknown 5 11%
Readers by discipline Count As %
Agricultural and Biological Sciences 16 36%
Medicine and Dentistry 9 20%
Biochemistry, Genetics and Molecular Biology 8 18%
Immunology and Microbiology 4 9%
Psychology 1 2%
Other 1 2%
Unknown 6 13%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 7. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 19 October 2021.
All research outputs
#4,576,292
of 22,689,790 outputs
Outputs from Journal of Translational Medicine
#737
of 3,965 outputs
Outputs of similar age
#32,722
of 169,160 outputs
Outputs of similar age from Journal of Translational Medicine
#13
of 54 outputs
Altmetric has tracked 22,689,790 research outputs across all sources so far. Compared to these this one has done well and is in the 79th percentile: it's in the top 25% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 3,965 research outputs from this source. They typically receive a lot more attention than average, with a mean Attention Score of 10.5. This one has done well, scoring higher than 81% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 169,160 tracked outputs that were published within six weeks on either side of this one in any source. This one has done well, scoring higher than 80% of its contemporaries.
We're also able to compare this research output to 54 others from the same source and published within six weeks on either side of this one. This one has done well, scoring higher than 75% of its contemporaries.