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Recapitulation of Tumor Heterogeneity and Molecular Signatures in a 3D Brain Cancer Model with Decreased Sensitivity to Histone Deacetylase Inhibition

Overview of attention for article published in PLOS ONE, December 2012
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2 X users
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1 Facebook page

Citations

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45 Dimensions

Readers on

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132 Mendeley
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Title
Recapitulation of Tumor Heterogeneity and Molecular Signatures in a 3D Brain Cancer Model with Decreased Sensitivity to Histone Deacetylase Inhibition
Published in
PLOS ONE, December 2012
DOI 10.1371/journal.pone.0052335
Pubmed ID
Authors

Stuart J. Smith, Martin Wilson, Jennifer H. Ward, Cheryl V. Rahman, Andrew C. Peet, Donald C. Macarthur, Felicity R. A. J. Rose, Richard G. Grundy, Ruman Rahman

Abstract

Physiologically relevant pre-clinical ex vivo models recapitulating CNS tumor micro-environmental complexity will aid development of biologically-targeted agents. We present comprehensive characterization of tumor aggregates generated using the 3D Rotary Cell Culture System (RCCS).

X Demographics

X Demographics

The data shown below were collected from the profiles of 2 X users who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 132 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
United States 1 <1%
Unknown 131 99%

Demographic breakdown

Readers by professional status Count As %
Student > Ph. D. Student 35 27%
Researcher 23 17%
Student > Master 15 11%
Student > Doctoral Student 10 8%
Student > Bachelor 10 8%
Other 16 12%
Unknown 23 17%
Readers by discipline Count As %
Agricultural and Biological Sciences 27 20%
Biochemistry, Genetics and Molecular Biology 24 18%
Medicine and Dentistry 20 15%
Engineering 10 8%
Neuroscience 4 3%
Other 21 16%
Unknown 26 20%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 2. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 19 December 2012.
All research outputs
#14,740,534
of 22,689,790 outputs
Outputs from PLOS ONE
#123,008
of 193,655 outputs
Outputs of similar age
#175,129
of 280,030 outputs
Outputs of similar age from PLOS ONE
#2,805
of 4,862 outputs
Altmetric has tracked 22,689,790 research outputs across all sources so far. This one is in the 32nd percentile – i.e., 32% of other outputs scored the same or lower than it.
So far Altmetric has tracked 193,655 research outputs from this source. They typically receive a lot more attention than average, with a mean Attention Score of 15.0. This one is in the 33rd percentile – i.e., 33% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 280,030 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 35th percentile – i.e., 35% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 4,862 others from the same source and published within six weeks on either side of this one. This one is in the 38th percentile – i.e., 38% of its contemporaries scored the same or lower than it.