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X Demographics
Mendeley readers
Attention Score in Context
| Title |
A Specialized Microvascular Domain in the Mouse Neural Stem Cell Niche
|
|---|---|
| Published in |
PLOS ONE, January 2013
|
| DOI | 10.1371/journal.pone.0053546 |
| Pubmed ID | |
| Authors |
James C. Culver, Tegy J. Vadakkan, Mary E. Dickinson |
| Abstract |
The microenvironment of the subependymal zone (SEZ) neural stem cell niche is necessary for regulating adult neurogenesis. In particular, signaling from the microvasculature is essential for adult neural stem cell maintenance, but microvascular structure and blood flow dynamics in the SEZ are not well understood. In this work, we show that the mouse SEZ constitutes a specialized microvascular domain defined by unique vessel architecture and reduced rates of blood flow. Additionally, we demonstrate that hypoxic conditions are detectable in the ependymal layer that lines the ventricle, and in a subpopulation of neurons throughout the SEZ and striatum. Together, these data highlight previously unidentified features of the SEZ neural stem cell niche, and further demonstrate the extent of microvascular specialization in the SEZ microenvironment. |
X Demographics
The data shown below were collected from the profiles of 5 X users who shared this research output. Click here to find out more about how the information was compiled.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| United States | 2 | 40% |
| Unknown | 3 | 60% |
Demographic breakdown
| Type | Count | As % |
|---|---|---|
| Members of the public | 4 | 80% |
| Scientists | 1 | 20% |
Mendeley readers
The data shown below were compiled from readership statistics for 75 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Portugal | 1 | 1% |
| Germany | 1 | 1% |
| Chile | 1 | 1% |
| Brazil | 1 | 1% |
| United Kingdom | 1 | 1% |
| Canada | 1 | 1% |
| Denmark | 1 | 1% |
| Greece | 1 | 1% |
| Unknown | 67 | 89% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Student > Ph. D. Student | 17 | 23% |
| Researcher | 16 | 21% |
| Student > Master | 9 | 12% |
| Student > Bachelor | 6 | 8% |
| Professor > Associate Professor | 6 | 8% |
| Other | 12 | 16% |
| Unknown | 9 | 12% |
| Readers by discipline | Count | As % |
|---|---|---|
| Agricultural and Biological Sciences | 24 | 32% |
| Neuroscience | 14 | 19% |
| Biochemistry, Genetics and Molecular Biology | 7 | 9% |
| Medicine and Dentistry | 6 | 8% |
| Engineering | 5 | 7% |
| Other | 5 | 7% |
| Unknown | 14 | 19% |
Attention Score in Context
This research output has an Altmetric Attention Score of 4. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 08 January 2013.
All research outputs
#6,919,691
of 22,691,736 outputs
Outputs from PLOS ONE
#81,532
of 193,720 outputs
Outputs of similar age
#76,144
of 281,525 outputs
Outputs of similar age from PLOS ONE
#1,666
of 4,792 outputs
Altmetric has tracked 22,691,736 research outputs across all sources so far. This one has received more attention than most of these and is in the 68th percentile.
So far Altmetric has tracked 193,720 research outputs from this source. They typically receive a lot more attention than average, with a mean Attention Score of 15.0. This one has gotten more attention than average, scoring higher than 56% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 281,525 tracked outputs that were published within six weeks on either side of this one in any source. This one has gotten more attention than average, scoring higher than 71% of its contemporaries.
We're also able to compare this research output to 4,792 others from the same source and published within six weeks on either side of this one. This one has gotten more attention than average, scoring higher than 63% of its contemporaries.