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Mendeley readers
Attention Score in Context
| Title |
Leptin Resistance in Vagal Afferent Neurons Inhibits Cholecystokinin Signaling and Satiation in Diet Induced Obese Rats
|
|---|---|
| Published in |
PLOS ONE, March 2012
|
| DOI | 10.1371/journal.pone.0032967 |
| Pubmed ID | |
| Authors |
Guillaume de Lartigue, Claire Barbier de la Serre, Elvis Espero, Jennifer Lee, Helen E. Raybould |
| Abstract |
The gastrointestinal hormone cholecystokinin (CCK) plays an important role in regulating meal size and duration by activating CCK1 receptors on vagal afferent neurons (VAN). Leptin enhances CCK signaling in VAN via an early growth response 1 (EGR1) dependent pathway thereby increasing their sensitivity to CCK. In response to a chronic ingestion of a high fat diet, VAN develop leptin resistance and the satiating effects of CCK are reduced. We tested the hypothesis that leptin resistance in VAN is responsible for reducing CCK signaling and satiation. |
Mendeley readers
The data shown below were compiled from readership statistics for 100 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| United States | 2 | 2% |
| United Kingdom | 1 | 1% |
| Unknown | 97 | 97% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Student > Ph. D. Student | 17 | 17% |
| Student > Bachelor | 15 | 15% |
| Researcher | 12 | 12% |
| Student > Master | 12 | 12% |
| Student > Doctoral Student | 9 | 9% |
| Other | 19 | 19% |
| Unknown | 16 | 16% |
| Readers by discipline | Count | As % |
|---|---|---|
| Medicine and Dentistry | 22 | 22% |
| Agricultural and Biological Sciences | 19 | 19% |
| Biochemistry, Genetics and Molecular Biology | 9 | 9% |
| Neuroscience | 8 | 8% |
| Immunology and Microbiology | 5 | 5% |
| Other | 17 | 17% |
| Unknown | 20 | 20% |
Attention Score in Context
This research output has an Altmetric Attention Score of 2. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 13 March 2022.
All research outputs
#15,169,143
of 23,330,477 outputs
Outputs from PLOS ONE
#128,576
of 199,516 outputs
Outputs of similar age
#98,590
of 157,459 outputs
Outputs of similar age from PLOS ONE
#2,066
of 3,555 outputs
Altmetric has tracked 23,330,477 research outputs across all sources so far. This one is in the 32nd percentile – i.e., 32% of other outputs scored the same or lower than it.
So far Altmetric has tracked 199,516 research outputs from this source. They typically receive a lot more attention than average, with a mean Attention Score of 15.3. This one is in the 32nd percentile – i.e., 32% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 157,459 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 35th percentile – i.e., 35% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 3,555 others from the same source and published within six weeks on either side of this one. This one is in the 38th percentile – i.e., 38% of its contemporaries scored the same or lower than it.